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Discovery of a stable tripeptide targeting the N-domain of CRF1 receptor.
Liapakis G, Karageorgos V, Andreadelis I, Holz GG, Dermitzaki E, Kordopati GG, Stylos EΚ, Spyridaki K, Poulaki S, Ntountaniotis D, Sakellaris S, Vanioti M, Kostagianni A, Marousis KD, Leonis G, Kokotos G, Venihaki M, Spyroulias GA, Tselios T, Margioris A, Tzakos AG, Mavromoustakos T. Liapakis G, et al. Among authors: mavromoustakos t. Amino Acids. 2020 Sep;52(9):1337-1351. doi: 10.1007/s00726-020-02895-4. Epub 2020 Sep 29. Amino Acids. 2020. PMID: 32996057 Free PMC article.
Design and synthesis of a potent cyclic analogue of the myelin basic protein epitope MBP72-85: importance of the Ala81 carboxyl group and of a cyclic conformation for induction of experimental allergic encephalomyelitis.
Tselios T, Probert L, Daliani I, Matsoukas E, Troganis A, Gerothanassis IP, Mavromoustakos T, Moore GJ, Matsoukas JM. Tselios T, et al. Among authors: mavromoustakos t. J Med Chem. 1999 Apr 8;42(7):1170-7. doi: 10.1021/jm980250e. J Med Chem. 1999. PMID: 10197961
Treatment of experimental allergic encephalomyelitis (EAE) by a rationally designed cyclic analogue of myelin basic protein (MBP) epitope 72-85.
Tselios T, Daliani I, Deraos S, Thymianou S, Matsoukas E, Troganis A, Gerothanassis I, Mouzaki A, Mavromoustakos T, Probert L, Matsoukas J. Tselios T, et al. Among authors: mavromoustakos t. Bioorg Med Chem Lett. 2000 Dec 18;10(24):2713-7. doi: 10.1016/s0960-894x(00)00556-4. Bioorg Med Chem Lett. 2000. PMID: 11133075
A putative bioactive conformation for the altered peptide ligand of myelin basic protein and inhibitor of experimental autoimmune encephalomyelitis [Arg91, Ala96] MBP87-99.
Mantzourani ED, Tselios TV, Grdadolnik SG, Brancale A, Platts JA, Matsoukas JM, Mavromoustakos TM. Mantzourani ED, et al. Among authors: mavromoustakos tm. J Mol Graph Model. 2006 Sep;25(1):17-29. doi: 10.1016/j.jmgm.2005.09.010. Epub 2005 Nov 28. J Mol Graph Model. 2006. PMID: 16310386
243 results