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Leveraging NMR and X-ray Data of the Free Ligands to Build Better Drugs Targeting Angiotensin II Type 1 G-Protein Coupled Receptor.
Kellici TF, Ntountaniotis D, Kritsi E, Zervou M, Zoumpoulakis P, Potamitis C, Durdagi S, Salmas RE, Ergun G, Gokdemir E, Halabalaki M, Gerothanassis IP, Liapakis G, Tzakos A, Mavromoustakos T. Kellici TF, et al. Among authors: mavromoustakos t. Curr Med Chem. 2016;23(1):36-59. doi: 10.2174/0929867323666151117122116. Curr Med Chem. 2016. PMID: 26572611 Review.
Synthesis and contractile activities of cyclic thrombin receptor-derived peptide analogues with a Phe-Leu-Leu-Arg motif: importance of the Phe/Arg relative conformation and the primary amino group for activity.
Matsoukas JM, Panagiotopoulos D, Keramida M, Mavromoustakos T, Yamdagni R, Wu Q, Moore GJ, Saifeddine M, Hollenberg MD. Matsoukas JM, et al. Among authors: mavromoustakos t. J Med Chem. 1996 Aug 30;39(18):3585-91. doi: 10.1021/jm950690v. J Med Chem. 1996. PMID: 8784457
Design and synthesis of a potent cyclic analogue of the myelin basic protein epitope MBP72-85: importance of the Ala81 carboxyl group and of a cyclic conformation for induction of experimental allergic encephalomyelitis.
Tselios T, Probert L, Daliani I, Matsoukas E, Troganis A, Gerothanassis IP, Mavromoustakos T, Moore GJ, Matsoukas JM. Tselios T, et al. Among authors: mavromoustakos t. J Med Chem. 1999 Apr 8;42(7):1170-7. doi: 10.1021/jm980250e. J Med Chem. 1999. PMID: 10197961
Thermodynamic origin of cis/trans isomers of a proline-containing beta-turn model dipeptide in aqueous solution: a combined variable temperature 1H-NMR, two-dimensional 1H,1H gradient enhanced nuclear Overhauser effect spectroscopy (NOESY), one-dimensional steady-state intermolecular 13C,1H NOE, and molecular dynamics study.
Troganis A, Gerothanassis IP, Athanassiou Z, Mavromoustakos T, Hawkes GE, Sakarellos C. Troganis A, et al. Among authors: mavromoustakos t. Biopolymers. 2000 Jan;53(1):72-83. doi: 10.1002/(SICI)1097-0282(200001)53:1<72::AID-BIP7>3.0.CO;2-5. Biopolymers. 2000. PMID: 10644952
243 results