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Safety and preliminary efficacy on cognitive performance and adaptive functionality of epigallocatechin gallate (EGCG) in children with Down syndrome. A randomized phase Ib clinical trial (PERSEUS study).
Genet Med. 2022 Oct;24(10):2004-2013. doi: 10.1016/j.gim.2022.06.011. Epub 2022 Aug 11.
Genet Med. 2022.
PMID: 35951014
Free article.
Clinical Trial.
The conjugative DNA translocase TrwB is a structure-specific DNA-binding protein.
Matilla I, Alfonso C, Rivas G, Bolt EL, de la Cruz F, Cabezon E.
Matilla I, et al.
J Biol Chem. 2010 Jun 4;285(23):17537-44. doi: 10.1074/jbc.M109.084137. Epub 2010 Apr 6.
J Biol Chem. 2010.
PMID: 20375020
Free PMC article.
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Substrate translocation involves specific lysine residues of the central channel of the conjugative coupling protein TrwB.
Larrea D, de Paz HD, Matilla I, Guzmán-Herrador DL, Lasso G, de la Cruz F, Cabezón E, Llosa M.
Larrea D, et al. Among authors: matilla i.
Mol Genet Genomics. 2017 Oct;292(5):1037-1049. doi: 10.1007/s00438-017-1331-3. Epub 2017 Jun 8.
Mol Genet Genomics. 2017.
PMID: 28597316
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The hexameric structure of a conjugative VirB4 protein ATPase provides new insights for a functional and phylogenetic relationship with DNA translocases.
Peña A, Matilla I, Martín-Benito J, Valpuesta JM, Carrascosa JL, de la Cruz F, Cabezón E, Arechaga I.
Peña A, et al. Among authors: matilla i.
J Biol Chem. 2012 Nov 16;287(47):39925-32. doi: 10.1074/jbc.M112.413849. Epub 2012 Oct 3.
J Biol Chem. 2012.
PMID: 23035111
Free PMC article.
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Generation of the Antioxidant Hydroxytyrosol from Tyrosol Present in Beer and Red Wine in a Randomized Clinical Trial.
Soldevila-Domenech N, Boronat A, Mateus J, Diaz-Pellicer P, Matilla I, Pérez-Otero M, Aldea-Perona A, de la Torre R.
Soldevila-Domenech N, et al. Among authors: matilla i.
Nutrients. 2019 Sep 18;11(9):2241. doi: 10.3390/nu11092241.
Nutrients. 2019.
PMID: 31540384
Free PMC article.
Clinical Trial.
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The ATPase activity of the DNA transporter TrwB is modulated by protein TrwA: implications for a common assembly mechanism of DNA translocating motors.
Tato I, Matilla I, Arechaga I, Zunzunegui S, de la Cruz F, Cabezon E.
Tato I, et al. Among authors: matilla i.
J Biol Chem. 2007 Aug 31;282(35):25569-76. doi: 10.1074/jbc.M703464200. Epub 2007 Jun 27.
J Biol Chem. 2007.
PMID: 17599913
Free article.
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