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Metal Complexes as Antifungals? From a Crowd-Sourced Compound Library to the First In Vivo Experiments.
Frei A, Elliott AG, Kan A, Dinh H, Bräse S, Bruce AE, Bruce MR, Chen F, Humaidy D, Jung N, King AP, Lye PG, Maliszewska HK, Mansour AM, Matiadis D, Muñoz MP, Pai TY, Pokhrel S, Sadler PJ, Sagnou M, Taylor M, Wilson JJ, Woods D, Zuegg J, Meyer W, Cain AK, Cooper MA, Blaskovich MAT. Frei A, et al. Among authors: matiadis d. JACS Au. 2022 Sep 23;2(10):2277-2294. doi: 10.1021/jacsau.2c00308. eCollection 2022 Oct 24. JACS Au. 2022. PMID: 36311838 Free PMC article.
Synthesis, biological evaluation and structure-activity relationships of 5-arylidene tetramic acids with antibacterial activity against methicillin-resistant Staphylococcus aureus.
Matiadis D, Tsironis D, Stefanou V, Boussias S, Panagiotopoulou A, McKee V, Igglessi-Markopoulou O, Markopoulos J. Matiadis D, et al. Bioorg Med Chem Lett. 2020 May 15;30(10):127107. doi: 10.1016/j.bmcl.2020.127107. Epub 2020 Mar 13. Bioorg Med Chem Lett. 2020. PMID: 32216991
Synthesis, characterization and antimicrobial activity of N-acetyl-3-acetyl-5-benzylidene tetramic acid-metal complexes. X-ray analysis and identification of the Cd(II) complex as a potent antifungal agent.
Matiadis D, Tsironis D, Stefanou V, Elliott AG, Kordatos K, Zahariou G, Ioannidis N, McKee V, Panagiotopoulou A, Igglessi-Markopoulou O, Markopoulos J. Matiadis D, et al. J Inorg Biochem. 2019 May;194:65-73. doi: 10.1016/j.jinorgbio.2019.02.008. Epub 2019 Feb 21. J Inorg Biochem. 2019. PMID: 30831391
18 results