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Genetic variation in the SIM1 locus is associated with erectile dysfunction.
Jorgenson E, Matharu N, Palmer MR, Yin J, Shan J, Hoffmann TJ, Thai KK, Zhou X, Hotaling JM, Jarvik GP, Ahituv N, Wessells H, Van Den Eeden SK. Jorgenson E, et al. Among authors: matharu n. Proc Natl Acad Sci U S A. 2018 Oct 23;115(43):11018-11023. doi: 10.1073/pnas.1809872115. Epub 2018 Oct 8. Proc Natl Acad Sci U S A. 2018. PMID: 30297428 Free PMC article.
Reply to Liu et al.: Tissue specificity of SIM1 gene expression and erectile dysfunction.
Jorgenson E, Matharu N, Palmer MR, Yin J, Shan J, Hoffmann TJ, Thai KK, Zhou X, Hotaling JM, Jarvik GP, Ahituv N, Wessells H, Van Den Eeden SK. Jorgenson E, et al. Among authors: matharu n. Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3349-3350. doi: 10.1073/pnas.1900162116. Epub 2019 Feb 12. Proc Natl Acad Sci U S A. 2019. PMID: 30755537 Free PMC article. No abstract available.
Modulating gene regulation to treat genetic disorders.
Matharu N, Ahituv N. Matharu N, et al. Nat Rev Drug Discov. 2020 Nov;19(11):757-775. doi: 10.1038/s41573-020-0083-7. Epub 2020 Oct 5. Nat Rev Drug Discov. 2020. PMID: 33020616 Review.
Oestrogen engages brain MC4R signalling to drive physical activity in female mice.
Krause WC, Rodriguez R, Gegenhuber B, Matharu N, Rodriguez AN, Padilla-Roger AM, Toma K, Herber CB, Correa SM, Duan X, Ahituv N, Tollkuhn J, Ingraham HA. Krause WC, et al. Among authors: matharu n. Nature. 2021 Nov;599(7883):131-135. doi: 10.1038/s41586-021-04010-3. Epub 2021 Oct 13. Nature. 2021. PMID: 34646010 Free PMC article.
Massively parallel jumping assay decodes Alu retrotransposition activity.
Matharu N, Zhao J, Sohota A, Deng L, Hung Y, Li Z, Sims J, Rattanasopha S, Meyer J, Carbone L, Kircher M, Ahituv N. Matharu N, et al. bioRxiv [Preprint]. 2024 Apr 19:2024.04.16.589814. doi: 10.1101/2024.04.16.589814. bioRxiv. 2024. PMID: 38659854 Free PMC article. Preprint.
31 results