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NEDD9 targets COL3A1 to promote endothelial fibrosis and pulmonary arterial hypertension.
Samokhin AO, Stephens T, Wertheim BM, Wang RS, Vargas SO, Yung LM, Cao M, Brown M, Arons E, Dieffenbach PB, Fewell JG, Matar M, Bowman FP, Haley KJ, Alba GA, Marino SM, Kumar R, Rosas IO, Waxman AB, Oldham WM, Khanna D, Graham BB, Seo S, Gladyshev VN, Yu PB, Fredenburgh LE, Loscalzo J, Leopold JA, Maron BA. Samokhin AO, et al. Among authors: matar m. Sci Transl Med. 2018 Jun 13;10(445):eaap7294. doi: 10.1126/scitranslmed.aap7294. Sci Transl Med. 2018. PMID: 29899023 Free PMC article.
Up-regulation of the mammalian target of rapamycin complex 1 subunit Raptor by aldosterone induces abnormal pulmonary artery smooth muscle cell survival patterns to promote pulmonary arterial hypertension.
Aghamohammadzadeh R, Zhang YY, Stephens TE, Arons E, Zaman P, Polach KJ, Matar M, Yung LM, Yu PB, Bowman FP, Opotowsky AR, Waxman AB, Loscalzo J, Leopold JA, Maron BA. Aghamohammadzadeh R, et al. Among authors: matar m. FASEB J. 2016 Jul;30(7):2511-27. doi: 10.1096/fj.201500042. Epub 2016 Mar 22. FASEB J. 2016. PMID: 27006450 Free PMC article.
Remodeled pulmonary arterioles from SU-5416/hypoxia-PAH rats and monocrotaline-PAH rats with hyperaldosteronism expressed increased levels of the Raptor target, p70S6K, which provided a basis for investigating aldosterone-Raptor signaling in human PASMCs. Aldosterone (10(-9) to 1 …
Remodeled pulmonary arterioles from SU-5416/hypoxia-PAH rats and monocrotaline-PAH rats with hyperaldosteronism expressed increased levels o …
Genetic and hypoxic alterations of the microRNA-210-ISCU1/2 axis promote iron-sulfur deficiency and pulmonary hypertension.
White K, Lu Y, Annis S, Hale AE, Chau BN, Dahlman JE, Hemann C, Opotowsky AR, Vargas SO, Rosas I, Perrella MA, Osorio JC, Haley KJ, Graham BB, Kumar R, Saggar R, Saggar R, Wallace WD, Ross DJ, Khan OF, Bader A, Gochuico BR, Matar M, Polach K, Johannessen NM, Prosser HM, Anderson DG, Langer R, Zweier JL, Bindoff LA, Systrom D, Waxman AB, Jin RC, Chan SY. White K, et al. Among authors: matar m. EMBO Mol Med. 2015 Jun;7(6):695-713. doi: 10.15252/emmm.201404511. EMBO Mol Med. 2015. PMID: 25825391 Free PMC article.
Synthetic tumor networks for screening drug delivery systems.
Prabhakarpandian B, Shen MC, Nichols JB, Garson CJ, Mills IR, Matar MM, Fewell JG, Pant K. Prabhakarpandian B, et al. Among authors: matar mm. J Control Release. 2015 Mar 10;201:49-55. doi: 10.1016/j.jconrel.2015.01.018. Epub 2015 Jan 17. J Control Release. 2015. PMID: 25599856 Free PMC article.
Versatile cationic lipids for siRNA delivery.
Sparks J, Slobodkin G, Matar M, Congo R, Ulkoski D, Rea-Ramsey A, Pence C, Rice J, McClure D, Polach KJ, Brunhoeber E, Wilkinson L, Wallace K, Anwer K, Fewell JG. Sparks J, et al. Among authors: matar m. J Control Release. 2012 Mar 10;158(2):269-76. doi: 10.1016/j.jconrel.2011.11.006. Epub 2011 Nov 12. J Control Release. 2012. PMID: 22100441
244 results