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Page 1
Effects of Conformational Changes in Peptide-CRM197 Conjugate Vaccines.
Jaffe J, Wucherer K, Sperry J, Zou Q, Chang Q, Massa MA, Bhattacharya K, Kumar S, Caparon M, Stead D, Wright P, Dirksen A, Francis MB. Jaffe J, et al. Among authors: massa ma. Bioconjug Chem. 2019 Jan 16;30(1):47-53. doi: 10.1021/acs.bioconjchem.8b00661. Epub 2018 Dec 12. Bioconjug Chem. 2019. PMID: 30475601
Discovery of N-(4-Fluoro-3-methoxybenzyl)-6-(2-(((2S,5R)-5-(hydroxymethyl)-1,4-dioxan-2-yl)methyl)-2H-tetrazol-5-yl)-2-methylpyrimidine-4-carboxamide. A Highly Selective and Orally Bioavailable Matrix Metalloproteinase-13 Inhibitor for the Potential Treatment of Osteoarthritis.
Ruminski PG, Massa M, Strohbach J, Hanau CE, Schmidt M, Scholten JA, Fletcher TR, Hamper BC, Carroll JN, Shieh HS, Caspers N, Collins B, Grapperhaus M, Palmquist KE, Collins J, Baldus JE, Hitchcock J, Kleine HP, Rogers MD, McDonald J, Munie GE, Messing DM, Portolan S, Whiteley LO, Sunyer T, Schnute ME. Ruminski PG, et al. J Med Chem. 2016 Jan 14;59(1):313-27. doi: 10.1021/acs.jmedchem.5b01434. Epub 2015 Dec 24. J Med Chem. 2016. PMID: 26653735
Discovery of a simple picomolar inhibitor of cholesteryl ester transfer protein.
Reinhard EJ, Wang JL, Durley RC, Fobian YM, Grapperhaus ML, Hickory BS, Massa MA, Norton MB, Promo MA, Tollefson MB, Vernier WF, Connolly DT, Witherbee BJ, Melton MA, Regina KJ, Smith ME, Sikorski JA. Reinhard EJ, et al. Among authors: massa ma. J Med Chem. 2003 May 22;46(11):2152-68. doi: 10.1021/jm020528+. J Med Chem. 2003. PMID: 12747787
Chiral N,N-disubstituted trifluoro-3-amino-2-propanols are potent inhibitors of cholesteryl ester transfer protein.
Durley RC, Grapperhaus ML, Hickory BS, Massa MA, Wang JL, Spangler DP, Mischke DA, Parnas BL, Fobian YM, Rath NP, Honda DD, Zeng M, Connolly DT, Heuvelman DM, Witherbee BJ, Melton MA, Glenn KC, Krul ES, Smith ME, Sikorski JA. Durley RC, et al. Among authors: massa ma. J Med Chem. 2002 Aug 29;45(18):3891-904. doi: 10.1021/jm020038h. J Med Chem. 2002. PMID: 12190312
Discovery of chiral N,N-disubstituted trifluoro-3-amino-2-propanols as potent inhibitors of cholesteryl ester transfer protein.
Durley RC, Grapperhaus ML, Massa MA, Mischke DA, Parnas BL, Fobian YM, Rath NP, Honda DD, Zeng M, Connolly DT, Heuvelman DM, Witherbee BJ, Glenn KC, Krul ES, Smith ME, Sikorski JA. Durley RC, et al. Among authors: massa ma. J Med Chem. 2000 Nov 30;43(24):4575-8. doi: 10.1021/jm000337b. J Med Chem. 2000. PMID: 11101348 No abstract available.
Inhibitors of lipoprotein(a) assembly.
Sexton KE, Lee HT, Massa M, Padia J, Patt WC, Liao P, Pontrello JK, Roth BD, Spahr MA, Ramharack R. Sexton KE, et al. Among authors: massa m. Bioorg Med Chem. 2003 Nov 3;11(22):4827-45. doi: 10.1016/j.bmc.2002.04.001. Bioorg Med Chem. 2003. PMID: 14556799
Butenolide endothelin antagonists with improved aqueous solubility.
Patt WC, Cheng XM, Repine JT, Lee C, Reisdorph BR, Massa MA, Doherty AM, Welch KM, Bryant JW, Flynn MA, Walker DM, Schroeder RL, Haleen SJ, Keiser JA. Patt WC, et al. Among authors: massa ma. J Med Chem. 1999 Jun 17;42(12):2162-8. doi: 10.1021/jm980504w. J Med Chem. 1999. PMID: 10377221
14 results