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Page 1
Targeting ApoE4/ApoE receptor LRP1 in Alzheimer's disease.
Martiskainen H, Haapasalo A, Kurkinen KM, Pihlajamäki J, Soininen H, Hiltunen M. Martiskainen H, et al. Expert Opin Ther Targets. 2013 Jul;17(7):781-94. doi: 10.1517/14728222.2013.789862. Epub 2013 Apr 11. Expert Opin Ther Targets. 2013. PMID: 23573918 Review.
Effects of NR1H3 genetic variation on the expression of liver X receptor α and the progression of Alzheimer's disease.
Natunen T, Martiskainen H, Sarajärvi T, Helisalmi S, Pursiheimo JP, Viswanathan J, Laitinen M, Mäkinen P, Kauppinen T, Rauramaa T, Leinonen V, Alafuzoff I, Haapasalo A, Soininen H, Hiltunen M. Natunen T, et al. Among authors: martiskainen h. PLoS One. 2013 Nov 20;8(11):e80700. doi: 10.1371/journal.pone.0080700. eCollection 2013. PLoS One. 2013. PMID: 24278306 Free PMC article.
High-fat diet increases tau expression in the brain of T2DM and AD mice independently of peripheral metabolic status.
Takalo M, Haapasalo A, Martiskainen H, Kurkinen KM, Koivisto H, Miettinen P, Khandelwal VK, Kemppainen S, Kaminska D, Mäkinen P, Leinonen V, Pihlajamäki J, Soininen H, Laakso M, Tanila H, Hiltunen M. Takalo M, et al. Among authors: martiskainen h. J Nutr Biochem. 2014 Jun;25(6):634-41. doi: 10.1016/j.jnutbio.2014.02.003. Epub 2014 Mar 12. J Nutr Biochem. 2014. PMID: 24746833
Effects of Alzheimer's disease-associated risk loci on cerebrospinal fluid biomarkers and disease progression: a polygenic risk score approach.
Martiskainen H, Helisalmi S, Viswanathan J, Kurki M, Hall A, Herukka SK, Sarajärvi T, Natunen T, Kurkinen KM, Huovinen J, Mäkinen P, Laitinen M, Koivisto AM, Mattila KM, Lehtimäki T, Remes AM, Leinonen V, Haapasalo A, Soininen H, Hiltunen M. Martiskainen H, et al. J Alzheimers Dis. 2015;43(2):565-73. doi: 10.3233/JAD-140777. J Alzheimers Dis. 2015. PMID: 25096612
Transcriptomics and mechanistic elucidation of Alzheimer's disease risk genes in the brain and in vitro models.
Martiskainen H, Viswanathan J, Nykänen NP, Kurki M, Helisalmi S, Natunen T, Sarajärvi T, Kurkinen KM, Pursiheimo JP, Rauramaa T, Alafuzoff I, Jääskeläinen JE, Leinonen V, Soininen H, Haapasalo A, Huttunen HJ, Hiltunen M. Martiskainen H, et al. Neurobiol Aging. 2015 Feb;36(2):1221.e15-28. doi: 10.1016/j.neurobiolaging.2014.09.003. Epub 2014 Sep 6. Neurobiol Aging. 2015. PMID: 25281018
DHCR24 exerts neuroprotection upon inflammation-induced neuronal death.
Martiskainen H, Paldanius KMA, Natunen T, Takalo M, Marttinen M, Leskelä S, Huber N, Mäkinen P, Bertling E, Dhungana H, Huuskonen M, Honkakoski P, Hotulainen P, Rilla K, Koistinaho J, Soininen H, Malm T, Haapasalo A, Hiltunen M. Martiskainen H, et al. J Neuroinflammation. 2017 Nov 7;14(1):215. doi: 10.1186/s12974-017-0991-6. J Neuroinflammation. 2017. PMID: 29115990 Free PMC article.
Decreased plasma C-reactive protein levels in APOE ε4 allele carriers.
Martiskainen H, Takalo M, Solomon A, Stančáková A, Marttinen M, Natunen T, Haapasalo A, Herukka SK, Kuusisto J, Soininen H, Kivipelto M, Laakso M, Hiltunen M. Martiskainen H, et al. Ann Clin Transl Neurol. 2018 Sep 17;5(10):1229-1240. doi: 10.1002/acn3.639. eCollection 2018 Oct. Ann Clin Transl Neurol. 2018. PMID: 30349858 Free PMC article.
The Alzheimer's disease-associated protective Plcγ2-P522R variant promotes immune functions.
Takalo M, Wittrahm R, Wefers B, Parhizkar S, Jokivarsi K, Kuulasmaa T, Mäkinen P, Martiskainen H, Wurst W, Xiang X, Marttinen M, Poutiainen P, Haapasalo A, Hiltunen M, Haass C. Takalo M, et al. Among authors: martiskainen h. Mol Neurodegener. 2020 Sep 11;15(1):52. doi: 10.1186/s13024-020-00402-7. Mol Neurodegener. 2020. PMID: 32917267 Free PMC article.
16 results