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Dietary Sargassum fusiforme improves memory and reduces amyloid plaque load in an Alzheimer's disease mouse model.
Bogie J, Hoeks C, Schepers M, Tiane A, Cuypers A, Leijten F, Chintapakorn Y, Suttiyut T, Pornpakakul S, Struik D, Kerksiek A, Liu HB, Hellings N, Martinez-Martinez P, Jonker JW, Dewachter I, Sijbrands E, Walter J, Hendriks J, Groen A, Staels B, Lütjohann D, Vanmierlo T, Mulder M. Bogie J, et al. Sci Rep. 2019 Mar 20;9(1):4908. doi: 10.1038/s41598-019-41399-4. Sci Rep. 2019. PMID: 30894635 Free PMC article.
Altered Sphingolipid Balance in Capillary Cerebral Amyloid Angiopathy.
de Wit NM, Snkhchyan H, den Hoedt S, Wattimena D, de Vos R, Mulder MT, Walter J, Martinez-Martinez P, Hoozemans JJ, Rozemuller AJ, de Vries HE. de Wit NM, et al. J Alzheimers Dis. 2017;60(3):795-807. doi: 10.3233/JAD-160551. J Alzheimers Dis. 2017. PMID: 27662305
Astrocytic ceramide as possible indicator of neuroinflammation.
de Wit NM, den Hoedt S, Martinez-Martinez P, Rozemuller AJ, Mulder MT, de Vries HE. de Wit NM, et al. J Neuroinflammation. 2019 Feb 25;16(1):48. doi: 10.1186/s12974-019-1436-1. J Neuroinflammation. 2019. PMID: 30803453 Free PMC article.
Sphingolipids in Alzheimer's disease, how can we target them?
Crivelli SM, Giovagnoni C, Visseren L, Scheithauer AL, de Wit N, den Hoedt S, Losen M, Mulder MT, Walter J, de Vries HE, Bieberich E, Martinez-Martinez P. Crivelli SM, et al. Adv Drug Deliv Rev. 2020;159:214-231. doi: 10.1016/j.addr.2019.12.003. Epub 2020 Jan 3. Adv Drug Deliv Rev. 2020. PMID: 31911096 Review.
Ceramide analog [18F]F-HPA-12 detects sphingolipid disbalance in the brain of Alzheimer's disease transgenic mice by functioning as a metabolic probe.
Crivelli SM, van Kruining D, Luo Q, Stevens JAA, Giovagnoni C, Paulus A, Bauwens M, Berkes D, de Vries HE, Mulder MT, Walter J, Waelkens E, Derua R, Swinnen JV, Dehairs J, Mottaghy FM, Losen M, Bieberich E, Martinez-Martinez P. Crivelli SM, et al. Sci Rep. 2020 Nov 9;10(1):19354. doi: 10.1038/s41598-020-76335-4. Sci Rep. 2020. PMID: 33168861 Free PMC article.
141 results