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Single-nucleus RNA-seq2 reveals functional crosstalk between liver zonation and ploidy.
Richter ML, Deligiannis IK, Yin K, Danese A, Lleshi E, Coupland P, Vallejos CA, Matchett KP, Henderson NC, Colome-Tatche M, Martinez-Jimenez CP. Richter ML, et al. Among authors: martinez jimenez cp. Nat Commun. 2021 Jul 12;12(1):4264. doi: 10.1038/s41467-021-24543-5. Nat Commun. 2021. PMID: 34253736 Free PMC article.
Hepatocyte-specific activity of TSC22D4 triggers progressive NAFLD by impairing mitochondrial function.
Wolff G, Sakurai M, Mhamane A, Troullinaki M, Maida A, Deligiannis IK, Yin K, Weber P, Morgenstern J, Wieder A, Kwon Y, Sekar R, Zeigerer A, Roden M, Blüher M, Volk N, Poth T, Hackert T, Wiedmann L, De Angelis Rigotti F, Rodriguez-Vita J, Fischer A, Mukthavaram R, Limphong P, Tachikawa K, Karmali P, Payne J, Chivukula P, Ekim-Üstünel B, Martinez-Jimenez CP, Szendrödi J, Nawroth P, Herzig S. Wolff G, et al. Among authors: martinez jimenez cp. Mol Metab. 2022 Jun;60:101487. doi: 10.1016/j.molmet.2022.101487. Epub 2022 Apr 1. Mol Metab. 2022. PMID: 35378329 Free PMC article.
Senescence-induced endothelial phenotypes underpin immune-mediated senescence surveillance.
Yin K, Patten D, Gough S, de Barros Gonçalves S, Chan A, Olan I, Cassidy L, Poblocka M, Zhu H, Lun A, Schuijs M, Young A, Martinez-Jimenez C, Halim TYF, Shetty S, Narita M, Hoare M. Yin K, et al. Genes Dev. 2022 May 1;36(9-10):533-549. doi: 10.1101/gad.349585.122. Epub 2022 May 26. Genes Dev. 2022. PMID: 35618311 Free PMC article.
Polyploidisation pleiotropically buffers ageing in hepatocytes.
Yin K, Büttner M, Deligiannis IK, Strzelecki M, Zhang L, Talavera-López C, Theis F, Odom DT, Martinez-Jimenez CP. Yin K, et al. Among authors: martinez jimenez cp. J Hepatol. 2024 Apr 5:S0168-8278(24)00227-7. doi: 10.1016/j.jhep.2024.03.043. Online ahead of print. J Hepatol. 2024. PMID: 38583492 Free article.
29 results