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Suppressing Hepatic UGT1A1 Increases Plasma Bilirubin, Lowers Plasma Urobilin, Reorganizes Kinase Signaling Pathways and Lipid Species and Improves Fatty Liver Disease.
Bates EA, Kipp ZA, Martinez GJ, Badmus OO, Soundarapandian MM, Foster D, Xu M, Creeden JF, Greer JR, Morris AJ, Stec DE, Hinds TD Jr. Bates EA, et al. Among authors: martinez gj. Biomolecules. 2023 Jan 29;13(2):252. doi: 10.3390/biom13020252. Biomolecules. 2023. PMID: 36830621 Free PMC article.
Hepatic kinome atlas: An in-depth identification of kinase pathways in liver fibrosis of humans and rodents.
Creeden JF, Kipp ZA, Xu M, Flight RM, Moseley HNB, Martinez GJ, Lee WH, Alganem K, Imami AS, McMullen MR, Roychowdhury S, Nawabi AM, Hipp JA, Softic S, Weinman SA, McCullumsmith R, Nagy LE, Hinds TD Jr. Creeden JF, et al. Among authors: martinez gj. Hepatology. 2022 Nov;76(5):1376-1388. doi: 10.1002/hep.32467. Epub 2022 Apr 8. Hepatology. 2022. PMID: 35313030 Free PMC article.
Loss of hepatic PPARα in mice causes hypertension and cardiovascular disease.
Badmus OO, Kipp ZA, Bates EA, da Silva AA, Taylor LC, Martinez GJ, Lee WH, Creeden JF, Hinds TD Jr, Stec DE. Badmus OO, et al. Among authors: martinez gj. Am J Physiol Regul Integr Comp Physiol. 2023 Jul 1;325(1):R81-R95. doi: 10.1152/ajpregu.00057.2023. Epub 2023 May 22. Am J Physiol Regul Integr Comp Physiol. 2023. PMID: 37212551
FOXS1 is increased in liver fibrosis and regulates TGFβ responsiveness and proliferation pathways in human hepatic stellate cells.
Bates EA, Kipp ZA, Lee WH, Martinez GJ, Weaver L, Becker KN, Pauss SN, Creeden JF, Anspach GB, Helsley RN, Xu M, Bruno MEC, Starr ME, Hinds TD Jr. Bates EA, et al. Among authors: martinez gj. J Biol Chem. 2024 Mar;300(3):105691. doi: 10.1016/j.jbc.2024.105691. Epub 2024 Jan 26. J Biol Chem. 2024. PMID: 38280429 Free PMC article.
Cutting Edge: Polycomb Repressive Complex 1 Subunit Cbx4 Positively Regulates Effector Responses in CD8 T Cells.
Melo GA, Xu T, Calôba C, Schutte A, Passos TO, Neto MAN, Brum G, Oliveira-Vieira B, Higa L, Monteiro FLL, Berbert L, Gonçalves ANA, Tanuri A, Viola JPB, Werneck MBF, Nakaya HI, Pipkin ME, Martinez GJ, Pereira RM. Melo GA, et al. Among authors: martinez gj. J Immunol. 2023 Sep 1;211(5):721-726. doi: 10.4049/jimmunol.2200757. J Immunol. 2023. PMID: 37486206 Free PMC article.
98 results