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63 results

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Page 1
BET Protein Inhibition for Pulmonary Arterial Hypertension: A Pilot Clinical Trial.
Provencher S, Potus F, Blais-Lecours P, Bernard S, Martineau S, Breuils-Bonnet S, Weatherald J, Sweeney M, Kulikowski E, Boucherat O, Bonnet S. Provencher S, et al. Among authors: martineau s. Am J Respir Crit Care Med. 2022 Jun 1;205(11):1357-1360. doi: 10.1164/rccm.202109-2182LE. Am J Respir Crit Care Med. 2022. PMID: 35289736 No abstract available.
Multicenter Preclinical Validation of BET Inhibition for the Treatment of Pulmonary Arterial Hypertension.
Van der Feen DE, Kurakula K, Tremblay E, Boucherat O, Bossers GPL, Szulcek R, Bourgeois A, Lampron MC, Habbout K, Martineau S, Paulin R, Kulikowski E, Jahagirdar R, Schalij I, Bogaard HJ, Bartelds B, Provencher S, Berger RMF, Bonnet S, Goumans MJ. Van der Feen DE, et al. Among authors: martineau s. Am J Respir Crit Care Med. 2019 Oct 1;200(7):910-920. doi: 10.1164/rccm.201812-2275OC. Am J Respir Crit Care Med. 2019. PMID: 31042405
Identification of Long Noncoding RNA H19 as a New Biomarker and Therapeutic Target in Right Ventricular Failure in Pulmonary Arterial Hypertension.
Omura J, Habbout K, Shimauchi T, Wu WH, Breuils-Bonnet S, Tremblay E, Martineau S, Nadeau V, Gagnon K, Mazoyer F, Perron J, Potus F, Lin JH, Zafar H, Kiely DG, Lawrie A, Archer SL, Paulin R, Provencher S, Boucherat O, Bonnet S. Omura J, et al. Among authors: martineau s. Circulation. 2020 Oct 13;142(15):1464-1484. doi: 10.1161/CIRCULATIONAHA.120.047626. Epub 2020 Jul 23. Circulation. 2020. PMID: 32698630
R-Crizotinib predisposes to and exacerbates pulmonary arterial hypertension in animal models.
Awada C, Grobs Y, Wu WH, Habbout K, Romanet C, Breuils-Bonnet S, Tremblay E, Martineau S, Paulin R, Bonnet S, Provencher S, Potus F, Boucherat O. Awada C, et al. Among authors: martineau s. Eur Respir J. 2021 May 13;57(5):2003271. doi: 10.1183/13993003.03271-2020. Print 2021 May. Eur Respir J. 2021. PMID: 33446610 Free article. No abstract available.
Implication of EZH2 in the Pro-Proliferative and Apoptosis-Resistant Phenotype of Pulmonary Artery Smooth Muscle Cells in PAH: A Transcriptomic and Proteomic Approach.
Habbout K, Omura J, Awada C, Bourgeois A, Grobs Y, Krishna V, Breuils-Bonnet S, Tremblay E, Mkannez G, Martineau S, Nadeau V, Roux-Dalvai F, Orcholski M, Jeyaseelan J, Gutstein D, Potus F, Provencher S, Bonnet S, Paulin R, Boucherat O. Habbout K, et al. Among authors: martineau s. Int J Mol Sci. 2021 Mar 15;22(6):2957. doi: 10.3390/ijms22062957. Int J Mol Sci. 2021. PMID: 33803922 Free PMC article.
Potential for inhibition of checkpoint kinases 1/2 in pulmonary fibrosis and secondary pulmonary hypertension.
Wu WH, Bonnet S, Shimauchi T, Toro V, Grobs Y, Romanet C, Bourgeois A, Vitry G, Omura J, Tremblay E, Nadeau V, Orcholski M, Breuils-Bonnet S, Martineau S, Ferraro P, Potus F, Paulin R, Provencher S, Boucherat O. Wu WH, et al. Among authors: martineau s. Thorax. 2022 Mar;77(3):247-258. doi: 10.1136/thoraxjnl-2021-217377. Epub 2021 Jul 5. Thorax. 2022. PMID: 34226205
PARP1-PKM2 Axis Mediates Right Ventricular Failure Associated With Pulmonary Arterial Hypertension.
Shimauchi T, Boucherat O, Yokokawa T, Grobs Y, Wu W, Orcholski M, Martineau S, Omura J, Tremblay E, Shimauchi K, Nadeau V, Breuils-Bonnet S, Paulin R, Potus F, Provencher S, Bonnet S. Shimauchi T, et al. Among authors: martineau s. JACC Basic Transl Sci. 2022 Mar 16;7(4):384-403. doi: 10.1016/j.jacbts.2022.01.005. eCollection 2022 Apr. JACC Basic Transl Sci. 2022. PMID: 35540097 Free PMC article.
Hypusine Signaling Promotes Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension.
Lemay SE, Grobs Y, Romanet C, Martineau S, Salem M, Shimauchi T, Breuils-Bonnet S, Bourgeois A, Théberge C, Pelletier A, Potus F, Provencher S, Bonnet S, Boucherat O. Lemay SE, et al. Among authors: martineau s. Am J Respir Crit Care Med. 2024 Jan 23. doi: 10.1164/rccm.202305-0909OC. Online ahead of print. Am J Respir Crit Care Med. 2024. PMID: 38261723
Time Is Running Out in Pulmonary Arterial Hypertension: The Epigenetic Clock Is Clicking.
El Kabbout R, Azhar N, Breuils-Bonnet S, Martineau S, Krishna V, Kalyana-Sundaram S, Boucherat O, Provencher S, Bonnet S, Potus F. El Kabbout R, et al. Among authors: martineau s. Am J Respir Cell Mol Biol. 2024 Feb;70(2):140-143. doi: 10.1165/rcmb.2023-0335LE. Am J Respir Cell Mol Biol. 2024. PMID: 38299796 No abstract available.
63 results