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Synthetic virology approaches to improve the safety and efficacy of oncolytic virus therapies.
Azad T, Rezaei R, Singaravelu R, Pelin A, Boulton S, Petryk J, Onsu KA, Martin NT, Hoskin V, Ghahremani M, Marotel M, Marius R, He X, Crupi MJF, Hoang HD, Nik-Akhtar A, Ahmadi M, Zamani NK, Golshani A, Alain T, Greer P, Ardolino M, Dickinson BC, Tai LH, Ilkow CS, Bell JC. Azad T, et al. Among authors: martin nt. Nat Commun. 2023 May 26;14(1):3035. doi: 10.1038/s41467-023-38651-x. Nat Commun. 2023. PMID: 37236967 Free PMC article.
Neoadjuvant oncolytic virotherapy before surgery sensitizes triple-negative breast cancer to immune checkpoint therapy.
Bourgeois-Daigneault MC, Roy DG, Aitken AS, El Sayes N, Martin NT, Varette O, Falls T, St-Germain LE, Pelin A, Lichty BD, Stojdl DF, Ungerechts G, Diallo JS, Bell JC. Bourgeois-Daigneault MC, et al. Among authors: martin nt. Sci Transl Med. 2018 Jan 3;10(422):eaao1641. doi: 10.1126/scitranslmed.aao1641. Sci Transl Med. 2018. PMID: 29298865
Implications for SARS-CoV-2 Vaccine Design: Fusion of Spike Glycoprotein Transmembrane Domain to Receptor-Binding Domain Induces Trimerization.
Azad T, Singaravelu R, Crupi MJF, Jamieson T, Dave J, Brown EEF, Rezaei R, Taha Z, Boulton S, Martin NT, Surendran A, Poutou J, Ghahremani M, Nouri K, Whelan JT, Duong J, Tucker S, Diallo JS, Bell JC, Ilkow CS. Azad T, et al. Among authors: martin nt. Membranes (Basel). 2020 Aug 30;10(9):215. doi: 10.3390/membranes10090215. Membranes (Basel). 2020. PMID: 32872641 Free PMC article.
Nanoluciferase complementation-based bioreporter reveals the importance of N-linked glycosylation of SARS-CoV-2 S for viral entry.
Azad T, Singaravelu R, Taha Z, Jamieson TR, Boulton S, Crupi MJF, Martin NT, Fekete EEF, Poutou J, Ghahremani M, Pelin A, Nouri K, Rezaei R, Marshall CB, Enomoto M, Arulanandam R, Alluqmani N, Samson R, Gingras AC, Cameron DW, Greer PA, Ilkow CS, Diallo JS, Bell JC. Azad T, et al. Among authors: martin nt. Mol Ther. 2021 Jun 2;29(6):1984-2000. doi: 10.1016/j.ymthe.2021.02.007. Epub 2021 Feb 10. Mol Ther. 2021. PMID: 33578036 Free PMC article.
Characterization of Critical Determinants of ACE2-SARS CoV-2 RBD Interaction.
Brown EEF, Rezaei R, Jamieson TR, Dave J, Martin NT, Singaravelu R, Crupi MJF, Boulton S, Tucker S, Duong J, Poutou J, Pelin A, Yasavoli-Sharahi H, Taha Z, Arulanandam R, Surendran A, Ghahremani M, Austin B, Matar C, Diallo JS, Bell JC, Ilkow CS, Azad T. Brown EEF, et al. Among authors: martin nt. Int J Mol Sci. 2021 Feb 25;22(5):2268. doi: 10.3390/ijms22052268. Int J Mol Sci. 2021. PMID: 33668756 Free PMC article.
Adjuvant oncolytic virotherapy for personalized anti-cancer vaccination.
Roy DG, Geoffroy K, Marguerie M, Khan ST, Martin NT, Kmiecik J, Bobbala D, Aitken AS, de Souza CT, Stephenson KB, Lichty BD, Auer RC, Stojdl DF, Bell JC, Bourgeois-Daigneault MC. Roy DG, et al. Among authors: martin nt. Nat Commun. 2021 May 11;12(1):2626. doi: 10.1038/s41467-021-22929-z. Nat Commun. 2021. PMID: 33976179 Free PMC article.
41 results