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Extra Virgin Olive Oil Contains a Phenolic Inhibitor of the Histone Demethylase LSD1/KDM1A.
Cuyàs E, Gumuzio J, Lozano-Sánchez J, Carreras D, Verdura S, Llorach-Parés L, Sanchez-Martinez M, Selga E, Pérez GJ, Scornik FS, Brugada R, Bosch-Barrera J, Segura-Carretero A, Martin ÁG, Encinar JA, Menendez JA. Cuyàs E, et al. Among authors: martin ag. Nutrients. 2019 Jul 19;11(7):1656. doi: 10.3390/nu11071656. Nutrients. 2019. PMID: 31331073 Free PMC article.
Extra-virgin olive oil contains a metabolo-epigenetic inhibitor of cancer stem cells.
Corominas-Faja B, Cuyàs E, Lozano-Sánchez J, Cufí S, Verdura S, Fernández-Arroyo S, Borrás-Linares I, Martin-Castillo B, Martin ÁG, Lupu R, Nonell-Canals A, Sanchez-Martinez M, Micol V, Joven J, Segura-Carretero A, Menendez JA. Corominas-Faja B, et al. Among authors: martin castillo b, martin ag. Carcinogenesis. 2018 Apr 5;39(4):601-613. doi: 10.1093/carcin/bgy023. Carcinogenesis. 2018. PMID: 29452350 Free PMC article.
The LSD1 inhibitor iadademstat (ORY-1001) targets SOX2-driven breast cancer stem cells: a potential epigenetic therapy in luminal-B and HER2-positive breast cancer subtypes.
Cuyàs E, Gumuzio J, Verdura S, Brunet J, Bosch-Barrera J, Martin-Castillo B, Alarcón T, Encinar JA, Martin ÁG, Menendez JA. Cuyàs E, et al. Among authors: martin castillo b, martin ag. Aging (Albany NY). 2020 Mar 18;12(6):4794-4814. doi: 10.18632/aging.102887. Epub 2020 Mar 18. Aging (Albany NY). 2020. PMID: 32191225 Free PMC article.
Mimetics of extra virgin olive oil phenols with anti-cancer stem cell activity.
Cuyàs E, Gumuzio J, Lozano-Sánchez J, Segura-Carretero A, Verdura S, Bosch-Barrera J, Martin-Castillo B, Nonell-Canals A, Llebaria A, Cabello S, Serra C, Sanchez-Martinez M, Martin ÁG, Menendez JA. Cuyàs E, et al. Among authors: martin castillo b, martin ag. Aging (Albany NY). 2020 Nov 9;12(21):21057-21075. doi: 10.18632/aging.202154. Epub 2020 Nov 9. Aging (Albany NY). 2020. PMID: 33168787 Free PMC article.
Linking Pluripotency Reprogramming and Cancer.
Iglesias JM, Gumuzio J, Martin AG. Iglesias JM, et al. Among authors: martin ag. Stem Cells Transl Med. 2017 Feb;6(2):335-339. doi: 10.5966/sctm.2015-0225. Epub 2016 Sep 20. Stem Cells Transl Med. 2017. PMID: 28191771 Free PMC article.
Mitostemness.
Cuyàs E, Verdura S, Folguera-Blasco N, Bastidas-Velez C, Martin ÁG, Alarcón T, Menendez JA. Cuyàs E, et al. Among authors: martin ag. Cell Cycle. 2018;17(8):918-926. doi: 10.1080/15384101.2018.1467679. Epub 2018 Jul 2. Cell Cycle. 2018. PMID: 29886796 Free PMC article. Review.
Nuclear reprogramming of luminal-like breast cancer cells generates Sox2-overexpressing cancer stem-like cellular states harboring transcriptional activation of the mTOR pathway.
Corominas-Faja B, Cufí S, Oliveras-Ferraros C, Cuyàs E, López-Bonet E, Lupu R, Alarcón T, Vellon L, Iglesias JM, Leis O, Martín ÁG, Vazquez-Martin A, Menendez JA. Corominas-Faja B, et al. Among authors: martin ag. Cell Cycle. 2013 Sep 15;12(18):3109-24. doi: 10.4161/cc.26173. Epub 2013 Aug 21. Cell Cycle. 2013. PMID: 23974095 Free PMC article.
186 results