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A Phase I Expansion Cohort Study Evaluating the Safety and Efficacy of the CHK1 Inhibitor LY2880070 with Low-dose Gemcitabine in Patients with Metastatic Pancreatic Adenocarcinoma.
Clin Cancer Res. 2023 Dec 15;29(24):5047-5056. doi: 10.1158/1078-0432.CCR-23-2005.
Clin Cancer Res. 2023.
PMID: 37819936
CCAR2 functions downstream of the Shieldin complex to promote double-strand break end-joining.
Iyer DR, Harada N, Clairmont C, Jiang L, Martignetti D, Nguyen H, He YJ, Chowdhury D, D'Andrea AD.
Iyer DR, et al.
Proc Natl Acad Sci U S A. 2022 Dec 6;119(49):e2214935119. doi: 10.1073/pnas.2214935119. Epub 2022 Nov 29.
Proc Natl Acad Sci U S A. 2022.
PMID: 36442094
Free PMC article.
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TGFβ pathway is required for viable gestation of Fanconi anemia embryos.
Rodríguez A, Epperly M, Filiatrault J, Velázquez M, Yang C, McQueen K, Sambel LA, Nguyen H, Iyer DR, Juárez U, Ayala-Zambrano C, Martignetti DB, Frías S, Fisher R, Parmar K, Greenberger JS, D'Andrea AD.
Rodríguez A, et al. Among authors: martignetti db.
PLoS Genet. 2022 Nov 28;18(11):e1010459. doi: 10.1371/journal.pgen.1010459. eCollection 2022 Nov.
PLoS Genet. 2022.
PMID: 36441774
Free PMC article.
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