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Evolution of protein interfaces in multimers and fibrils.
Zabel WJ, Hagner KP, Livesey BJ, Marsh JA, Setayeshgar S, Lynch M, Higgs PG. Zabel WJ, et al. Among authors: marsh ja. J Chem Phys. 2019 Jun 14;150(22):225102. doi: 10.1063/1.5086042. J Chem Phys. 2019. PMID: 31202237 Free PMC article.
Recurrent heterozygous PAX6 missense variants cause severe bilateral microphthalmia via predictable effects on DNA-protein interaction.
Williamson KA, Hall HN, Owen LJ, Livesey BJ, Hanson IM, Adams GGW, Bodek S, Calvas P, Castle B, Clarke M, Deng AT, Edery P, Fisher R, Gillessen-Kaesbach G, Heon E, Hurst J, Josifova D, Lorenz B, McKee S, Meire F, Moore AT, Parker M, Reiff CM, Self J, Tobias ES, Verheij JBGM, Willems M, Williams D, van Heyningen V, Marsh JA, FitzPatrick DR. Williamson KA, et al. Among authors: marsh ja. Genet Med. 2020 Mar;22(3):598-609. doi: 10.1038/s41436-019-0685-9. Epub 2019 Nov 8. Genet Med. 2020. PMID: 31700164 Free PMC article.
The properties of human disease mutations at protein interfaces.
Livesey BJ, Marsh JA. Livesey BJ, et al. Among authors: marsh ja. PLoS Comput Biol. 2022 Feb 4;18(2):e1009858. doi: 10.1371/journal.pcbi.1009858. eCollection 2022 Feb. PLoS Comput Biol. 2022. PMID: 35120134 Free PMC article.
Longitudinal dynamics of clonal hematopoiesis identifies gene-specific fitness effects.
Robertson NA, Latorre-Crespo E, Terradas-Terradas M, Lemos-Portela J, Purcell AC, Livesey BJ, Hillary RF, Murphy L, Fawkes A, MacGillivray L, Copland M, Marioni RE, Marsh JA, Harris SE, Cox SR, Deary IJ, Schumacher LJ, Kirschner K, Chandra T. Robertson NA, et al. Among authors: marsh ja. Nat Med. 2022 Jul;28(7):1439-1446. doi: 10.1038/s41591-022-01883-3. Epub 2022 Jul 4. Nat Med. 2022. PMID: 35788175 Free PMC article.
237 results