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Unraveling tumor-immune heterogeneity in advanced ovarian cancer uncovers immunogenic effect of chemotherapy.
Jiménez-Sánchez A, Cybulska P, Mager KL, Koplev S, Cast O, Couturier DL, Memon D, Selenica P, Nikolovski I, Mazaheri Y, Bykov Y, Geyer FC, Macintyre G, Gavarró LM, Drews RM, Gill MB, Papanastasiou AD, Sosa RE, Soslow RA, Walther T, Shen R, Chi DS, Park KJ, Hollmann T, Reis-Filho JS, Markowetz F, Beltrao P, Vargas HA, Zamarin D, Brenton JD, Snyder A, Weigelt B, Sala E, Miller ML. Jiménez-Sánchez A, et al. Among authors: markowetz f. Nat Genet. 2020 Jun;52(6):582-593. doi: 10.1038/s41588-020-0630-5. Epub 2020 Jun 1. Nat Genet. 2020. PMID: 32483290 Free PMC article.
The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups.
Curtis C, Shah SP, Chin SF, Turashvili G, Rueda OM, Dunning MJ, Speed D, Lynch AG, Samarajiwa S, Yuan Y, Gräf S, Ha G, Haffari G, Bashashati A, Russell R, McKinney S; METABRIC Group; Langerød A, Green A, Provenzano E, Wishart G, Pinder S, Watson P, Markowetz F, Murphy L, Ellis I, Purushotham A, Børresen-Dale AL, Brenton JD, Tavaré S, Caldas C, Aparicio S. Curtis C, et al. Among authors: markowetz f. Nature. 2012 Apr 18;486(7403):346-52. doi: 10.1038/nature10983. Nature. 2012. PMID: 22522925 Free PMC article.
Dissecting cancer heterogeneity--an unsupervised classification approach.
Wang X, Markowetz F, De Sousa E Melo F, Medema JP, Vermeulen L. Wang X, et al. Among authors: markowetz f. Int J Biochem Cell Biol. 2013 Nov;45(11):2574-9. doi: 10.1016/j.biocel.2013.08.014. Epub 2013 Sep 1. Int J Biochem Cell Biol. 2013. PMID: 24004832 Review.
Phylogenetic quantification of intra-tumour heterogeneity.
Schwarz RF, Trinh A, Sipos B, Brenton JD, Goldman N, Markowetz F. Schwarz RF, et al. Among authors: markowetz f. PLoS Comput Biol. 2014 Apr 17;10(4):e1003535. doi: 10.1371/journal.pcbi.1003535. eCollection 2014 Apr. PLoS Comput Biol. 2014. PMID: 24743184 Free PMC article.
A tumor DNA complex aberration index is an independent predictor of survival in breast and ovarian cancer.
Vollan HK, Rueda OM, Chin SF, Curtis C, Turashvili G, Shah S, Lingjærde OC, Yuan Y, Ng CK, Dunning MJ, Dicks E, Provenzano E, Sammut S, McKinney S, Ellis IO, Pinder S, Purushotham A, Murphy LC, Kristensen VN; METABRIC Group; Brenton JD, Pharoah PD, Børresen-Dale AL, Aparicio S, Caldas C. Vollan HK, et al. Mol Oncol. 2015 Jan;9(1):115-27. doi: 10.1016/j.molonc.2014.07.019. Epub 2014 Aug 8. Mol Oncol. 2015. PMID: 25169931 Free PMC article.
Spatial and temporal heterogeneity in high-grade serous ovarian cancer: a phylogenetic analysis.
Schwarz RF, Ng CK, Cooke SL, Newman S, Temple J, Piskorz AM, Gale D, Sayal K, Murtaza M, Baldwin PJ, Rosenfeld N, Earl HM, Sala E, Jimenez-Linan M, Parkinson CA, Markowetz F, Brenton JD. Schwarz RF, et al. Among authors: markowetz f. PLoS Med. 2015 Feb 24;12(2):e1001789. doi: 10.1371/journal.pmed.1001789. eCollection 2015 Feb. PLoS Med. 2015. PMID: 25710373 Free PMC article.
How Subclonal Modeling Is Changing the Metastatic Paradigm.
Macintyre G, Van Loo P, Corcoran NM, Wedge DC, Markowetz F, Hovens CM. Macintyre G, et al. Among authors: markowetz f. Clin Cancer Res. 2017 Feb 1;23(3):630-635. doi: 10.1158/1078-0432.CCR-16-0234. Epub 2016 Nov 18. Clin Cancer Res. 2017. PMID: 27864419 Review.
145 results