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PARP14 inhibition restores PD-1 immune checkpoint inhibitor response following IFNγ-driven acquired resistance in preclinical cancer models.
Wong CW, Evangelou C, Sefton KN, Leshem R, Zhang W, Gopalan V, Chattrakarn S, Fernandez Carro ML, Uzuner E, Mole H, Wilcock DJ, Smith MP, Sergiou K, Telfer BA, Isaac DT, Liu C, Perl NR, Marie K, Lorigan P, Williams KJ, Rao PE, Nagaraju RT, Niepel M, Hurlstone AFL. Wong CW, et al. Among authors: marie k. Nat Commun. 2023 Sep 26;14(1):5983. doi: 10.1038/s41467-023-41737-1. Nat Commun. 2023. PMID: 37752135 Free PMC article.
Gut microbiota dependent anti-tumor immunity restricts melanoma growth in Rnf5-/- mice.
Li Y, Tinoco R, Elmén L, Segota I, Xian Y, Fujita Y, Sahu A, Zarecki R, Marie K, Feng Y, Khateb A, Frederick DT, Ashkenazi SK, Kim H, Perez EG, Day CP, Segura Muñoz RS, Schmaltz R, Yooseph S, Tam MA, Zhang T, Avitan-Hersh E, Tzur L, Roizman S, Boyango I, Bar-Sela G, Orian A, Kaufman RJ, Bosenberg M, Goding CR, Baaten B, Levesque MP, Dummer R, Brown K, Merlino G, Ruppin E, Flaherty K, Ramer-Tait A, Long T, Peterson SN, Bradley LM, Ronai ZA. Li Y, et al. Among authors: marie k. Nat Commun. 2019 Apr 2;10(1):1492. doi: 10.1038/s41467-019-09525-y. Nat Commun. 2019. PMID: 30940817 Free PMC article.
Multimodel preclinical platform predicts clinical response of melanoma to immunotherapy.
Pérez-Guijarro E, Yang HH, Araya RE, El Meskini R, Michael HT, Vodnala SK, Marie KL, Smith C, Chin S, Lam KC, Thorkelsson A, Iacovelli AJ, Kulaga A, Fon A, Michalowski AM, Hugo W, Lo RS, Restifo NP, Sharan SK, Van Dyke T, Goldszmid RS, Weaver Ohler Z, Lee MP, Day CP, Merlino G. Pérez-Guijarro E, et al. Among authors: marie kl. Nat Med. 2020 May;26(5):781-791. doi: 10.1038/s41591-020-0818-3. Epub 2020 Apr 13. Nat Med. 2020. PMID: 32284588 Free PMC article.
Noncoding RNA circuitry in melanoma onset, plasticity, and therapeutic response.
Grafanaki K, Grammatikakis I, Ghosh A, Gopalan V, Olgun G, Liu H, Kyriakopoulos GC, Skeparnias I, Georgiou S, Stathopoulos C, Hannenhalli S, Merlino G, Marie KL, Day CP. Grafanaki K, et al. Among authors: marie kl. Pharmacol Ther. 2023 Aug;248:108466. doi: 10.1016/j.pharmthera.2023.108466. Epub 2023 Jun 8. Pharmacol Ther. 2023. PMID: 37301330 Free PMC article. Review.
Melanoma models for the next generation of therapies.
Patton EE, Mueller KL, Adams DJ, Anandasabapathy N, Aplin AE, Bertolotto C, Bosenberg M, Ceol CJ, Burd CE, Chi P, Herlyn M, Holmen SL, Karreth FA, Kaufman CK, Khan S, Kobold S, Leucci E, Levy C, Lombard DB, Lund AW, Marie KL, Marine JC, Marais R, McMahon M, Robles-Espinoza CD, Ronai ZA, Samuels Y, Soengas MS, Villanueva J, Weeraratna AT, White RM, Yeh I, Zhu J, Zon LI, Hurlbert MS, Merlino G. Patton EE, et al. Among authors: marie kl. Cancer Cell. 2021 May 10;39(5):610-631. doi: 10.1016/j.ccell.2021.01.011. Epub 2021 Feb 4. Cancer Cell. 2021. PMID: 33545064 Free PMC article. Review.
Melanoblast transcriptome analysis reveals pathways promoting melanoma metastasis.
Marie KL, Sassano A, Yang HH, Michalowski AM, Michael HT, Guo T, Tsai YC, Weissman AM, Lee MP, Jenkins LM, Zaidi MR, Pérez-Guijarro E, Day CP, Ylaya K, Hewitt SM, Patel NL, Arnheiter H, Davis S, Meltzer PS, Merlino G, Mishra PJ. Marie KL, et al. Nat Commun. 2020 Jan 16;11(1):333. doi: 10.1038/s41467-019-14085-2. Nat Commun. 2020. PMID: 31949145 Free PMC article.
Melanoma clonal subline analysis uncovers heterogeneity-driven immunotherapy resistance mechanisms.
Gruen C, Yang HH, Sassano A, Wu E, Gopalan V, Marie KL, Castro A, Mehrabadi FR, Wu CH, Church I, Needle GA, Smith C, Chin S, Ebersole J, Marcelus C, Fon A, Liu H, Malikic S, Sahinalp C, Carter H, Hannenhalli S, Day CP, Lee MP, Merlino G, Pérez-Guijarro E. Gruen C, et al. Among authors: marie kl. bioRxiv [Preprint]. 2023 Apr 5:2023.04.03.535074. doi: 10.1101/2023.04.03.535074. bioRxiv. 2023. PMID: 37333132 Free PMC article. Preprint.
Author Correction: Multimodel preclinical platform predicts clinical response of melanoma to immunotherapy.
Pérez-Guijarro E, Yang HH, Araya RE, El Meskini R, Michael HT, Vodnala SK, Marie KL, Smith C, Chin S, Lam KC, Thorkelsson A, Iacovelli AJ, Kulaga A, Fon A, Michalowski AM, Hugo W, Lo RS, Restifo NP, Sharan SK, Van Dyke T, Goldszmid RS, Weaver Ohler Z, Lee MP, Day CP, Merlino G. Pérez-Guijarro E, et al. Among authors: marie kl. Nat Med. 2021 Feb;27(2):355. doi: 10.1038/s41591-021-01252-6. Nat Med. 2021. PMID: 33514948 No abstract available.
Fast intratumor heterogeneity inference from single-cell sequencing data.
Kızılkale C, Rashidi Mehrabadi F, Sadeqi Azer E, Pérez-Guijarro E, Marie KL, Lee MP, Day CP, Merlino G, Ergün F, Buluç A, Sahinalp SC, Malikić S. Kızılkale C, et al. Among authors: marie kl. Nat Comput Sci. 2022 Sep;2(9):577-583. doi: 10.1038/s43588-022-00298-x. Epub 2022 Sep 8. Nat Comput Sci. 2022. PMID: 38177468 Free PMC article.
33 results