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8-Hydroxyquinolylnitrones as multifunctional ligands for the therapy of neurodegenerative diseases.
Knez D, Diez-Iriepa D, Chioua M, Gottinger A, Denic M, Chantegreil F, Nachon F, Brazzolotto X, Skrzypczak-Wiercioch A, Meden A, Pišlar A, Kos J, Žakelj S, Stojan J, Sałat K, Serrano J, Fernández AP, Sánchez-García A, Martínez-Murillo R, Binda C, López-Muñoz F, Gobec S, Marco-Contelles J. Knez D, et al. Among authors: marco contelles j. Acta Pharm Sin B. 2023 May;13(5):2152-2175. doi: 10.1016/j.apsb.2023.01.013. Epub 2023 Jan 19. Acta Pharm Sin B. 2023. PMID: 37250172 Free PMC article.
Multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease: design, synthesis, biochemical evaluation, ADMET, molecular modeling, and QSAR analysis of novel donepezil-pyridyl hybrids.
Bautista-Aguilera OM, Esteban G, Chioua M, Nikolic K, Agbaba D, Moraleda I, Iriepa I, Soriano E, Samadi A, Unzeta M, Marco-Contelles J. Bautista-Aguilera OM, et al. Drug Des Devel Ther. 2014 Oct 13;8:1893-910. doi: 10.2147/DDDT.S69258. eCollection 2014. Drug Des Devel Ther. 2014. PMID: 25378907 Free PMC article.
The reaction of 2-amino-4H-pyrans with N-bromosuccinimide.
Samadi A, Silva D, Chioua M, Infantes L, Soriano E, Marco-Contelles J. Samadi A, et al. Mol Divers. 2015 Feb;19(1):103-22. doi: 10.1007/s11030-014-9560-4. Epub 2014 Dec 14. Mol Divers. 2015. PMID: 25502233
CholesteroNitrones for Stroke.
Ayuso MI, Chioua M, Martínez-Alonso E, Soriano E, Montaner J, Masjuán J, Hadjipavlou-Litina DJ, Marco-Contelles J, Alcázar A. Ayuso MI, et al. J Med Chem. 2015 Aug 27;58(16):6704-9. doi: 10.1021/acs.jmedchem.5b00755. Epub 2015 Aug 13. J Med Chem. 2015. PMID: 26241908
Synthesis and Biological Assessment of Racemic Benzochromenopyrimidinimines as Antioxidant, Cholinesterase, and Aβ1-42 Aggregation Inhibitors for Alzheimer's Disease Therapy.
Dgachi Y, Ismaili L, Knez D, Benchekroun M, Martin H, Szałaj N, Wehle S, Bautista-Aguilera OM, Luzet V, Bonnet A, Malawska B, Gobec S, Chioua M, Decker M, Chabchoub F, Marco-Contelles J. Dgachi Y, et al. ChemMedChem. 2016 Jun 20;11(12):1318-27. doi: 10.1002/cmdc.201500539. Epub 2016 Jan 25. ChemMedChem. 2016. PMID: 26804623
Synthesis and Biological Evaluation of Benzochromenopyrimidinones as Cholinesterase Inhibitors and Potent Antioxidant, Non-Hepatotoxic Agents for Alzheimer's Disease.
Dgachi Y, Bautista-Aguilera OM, Benchekroun M, Martin H, Bonet A, Knez D, Godyń J, Malawska B, Gobec S, Chioua M, Janockova J, Soukup O, Chabchoub F, Marco-Contelles J, Ismaili L. Dgachi Y, et al. Molecules. 2016 May 14;21(5):634. doi: 10.3390/molecules21050634. Molecules. 2016. PMID: 27187348 Free PMC article.
217 results