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Resistance to integrase inhibitors.
Métifiot M, Marchand C, Maddali K, Pommier Y. Métifiot M, et al. Among authors: marchand c. Viruses. 2010 Jun 25;2(7):1347-66. doi: 10.3390/v2071347. Viruses. 2010. PMID: 20706558 Free PMC article.
Integrase inhibitors to treat HIV/AIDS.
Pommier Y, Johnson AA, Marchand C. Pommier Y, et al. Among authors: marchand c. Nat Rev Drug Discov. 2005 Mar;4(3):236-48. doi: 10.1038/nrd1660. Nat Rev Drug Discov. 2005. PMID: 15729361 Review.
HIV-1 IN inhibitors: 2010 update and perspectives.
Marchand C, Maddali K, Métifiot M, Pommier Y. Marchand C, et al. Curr Top Med Chem. 2009;9(11):1016-37. doi: 10.2174/156802609789630910. Curr Top Med Chem. 2009. PMID: 19747122 Free PMC article. Review.
Bicyclic hydroxy-1H-pyrrolopyridine-trione containing HIV-1 integrase inhibitors.
Zhao XZ, Maddali K, Metifiot M, Smith SJ, Vu BC, Marchand C, Hughes SH, Pommier Y, Burke TR Jr. Zhao XZ, et al. Among authors: marchand c. Chem Biol Drug Des. 2012 Feb;79(2):157-65. doi: 10.1111/j.1747-0285.2011.01270.x. Epub 2011 Dec 22. Chem Biol Drug Des. 2012. PMID: 22107736 Free PMC article.
6,7-Dihydroxy-1-oxoisoindoline-4-sulfonamide-containing HIV-1 integrase inhibitors.
Zhao XZ, Maddali K, Smith SJ, Métifiot M, Johnson BC, Marchand C, Hughes SH, Pommier Y, Burke TR Jr. Zhao XZ, et al. Among authors: marchand c. Bioorg Med Chem Lett. 2012 Dec 15;22(24):7309-13. doi: 10.1016/j.bmcl.2012.10.088. Epub 2012 Oct 27. Bioorg Med Chem Lett. 2012. PMID: 23149229 Free PMC article.
HIV integrase inhibitors: 20-year landmark and challenges.
Métifiot M, Marchand C, Pommier Y. Métifiot M, et al. Among authors: marchand c. Adv Pharmacol. 2013;67:75-105. doi: 10.1016/B978-0-12-405880-4.00003-2. Adv Pharmacol. 2013. PMID: 23885999 Free PMC article. Review.
Selectivity for strand-transfer over 3'-processing and susceptibility to clinical resistance of HIV-1 integrase inhibitors are driven by key enzyme-DNA interactions in the active site.
Métifiot M, Johnson BC, Kiselev E, Marler L, Zhao XZ, Burke TR Jr, Marchand C, Hughes SH, Pommier Y. Métifiot M, et al. Among authors: marchand c. Nucleic Acids Res. 2016 Aug 19;44(14):6896-906. doi: 10.1093/nar/gkw592. Epub 2016 Jul 1. Nucleic Acids Res. 2016. PMID: 27369381 Free PMC article.
492 results