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Page 1
The arylpiperazine derivatives N-(4-cyanophenylmethyl)-4-(2-diphenyl)-1-piperazinehexanamide and N-benzyl-4-(2-diphenyl)-1-piperazinehexanamide exert a long-lasting inhibition of human serotonin 5-HT7 receptor binding and cAMP signaling.
Atanes P, Lacivita E, Rodríguez J, Brea J, Burgueño J, Vela JM, Cadavid MI, Loza MI, Leopoldo M, Castro M. Atanes P, et al. Among authors: cadavid mi. Pharmacol Res Perspect. 2013 Dec;1(2):e00013. doi: 10.1002/prp2.13. Epub 2013 Dec 5. Pharmacol Res Perspect. 2013. PMID: 25505568 Free PMC article.
Modulation of cAMP-specific PDE without emetogenic activity: new sulfide-like PDE7 inhibitors.
García AM, Brea J, Morales-García JA, Perez DI, González A, Alonso-Gil S, Gracia-Rubio I, Ros-Simó C, Conde S, Cadavid MI, Loza MI, Perez-Castillo A, Valverde O, Martinez A, Gil C. García AM, et al. Among authors: cadavid mi. J Med Chem. 2014 Oct 23;57(20):8590-607. doi: 10.1021/jm501090m. Epub 2014 Oct 8. J Med Chem. 2014. PMID: 25264825
Synthesis and allosteric modulation of the dopamine receptor by peptide analogs of L-prolyl-L-leucyl-glycinamide (PLG) modified in the L-proline or L-proline and L-leucine scaffolds.
Ferreira da Costa J, Caamaño O, Fernández F, García-Mera X, Sampaio-Dias IE, Brea JM, Cadavid MI. Ferreira da Costa J, et al. Among authors: cadavid mi. Eur J Med Chem. 2013 Nov;69:146-58. doi: 10.1016/j.ejmech.2013.08.001. Epub 2013 Aug 22. Eur J Med Chem. 2013. PMID: 24013414
28 results