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Diphenylene Iodonium as a Prominent Halogen Bond donor: The case of Human Monoamine Oxidase B.
Piña MLN, Bauzá A. Piña MLN, et al. Chemphyschem. 2024 Apr 30:e202400161. doi: 10.1002/cphc.202400161. Online ahead of print. Chemphyschem. 2024. PMID: 38687202
Herein we have investigated the formation and interplay of several noncovalent interactions (NCIs) involved in the inhibition of human monoamine oxidase B (MAO B). Concretely, an inspection of the Protein Data Bank (PDB) revealed the formation of a hal …
Herein we have investigated the formation and interplay of several noncovalent interactions (NCIs) involved in the inhibition of human mo …
Neurotherapeutic effects of quercetin-loaded nanoparticles and Biochanin-A extracted from Trifolium alexandrinum on PI3K/Akt/GSK-3β signaling in the cerebral cortex of male diabetic rats.
Newairy AA, Hamaad FA, Wahby MM, Ghoneum M, Abdou HM. Newairy AA, et al. PLoS One. 2024 Apr 29;19(4):e0301355. doi: 10.1371/journal.pone.0301355. eCollection 2024. PLoS One. 2024. PMID: 38683825 Free PMC article.
In addition, these treatments improved neurochemical levels, including acetylcholine, dopamine, and serotonin levels as well acetylcholinesterase and monoamine oxidase activities. Furthermore, these treatments lowered proinflammatory cytokine production for TNF-alph …
In addition, these treatments improved neurochemical levels, including acetylcholine, dopamine, and serotonin levels as well acetylcholinest …
Cannabidiol disrupts tryptophan metabolism in the human term placenta.
Portillo R, Abad C, Synova T, Kastner P, Heblik D, Kucera R, Karahoda R, Staud F. Portillo R, et al. Toxicology. 2024 Apr 23;505:153813. doi: 10.1016/j.tox.2024.153813. Online ahead of print. Toxicology. 2024. PMID: 38663822 Free article.
Explants were exposed to CBD at therapeutic (0.1, 1, 2.5 mug/ml) and non-therapeutic (20 and 40 mug/ml) concentrations to determine its effects on the gene and protein expression of key enzymes in TRP metabolism and metabolite release. CBD upregulated TRP hydroxylase (TPH) and do …
Explants were exposed to CBD at therapeutic (0.1, 1, 2.5 mug/ml) and non-therapeutic (20 and 40 mug/ml) concentrations to determine its effe …
PINK1 Type of Young-Onset Parkinson Disease.
Lange LM, Klein C. Lange LM, et al. 2010 Mar 16 [updated 2024 Apr 25]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. 2010 Mar 16 [updated 2024 Apr 25]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. PMID: 20301792 Free Books & Documents. Review.
MANAGEMENT: Treatment of manifestations: PINK1 type of young-onset Parkinson disease usually responds well to L-dopa and/or other dopamine agonists, which may be used in combination with catechol-O-methyltransferase inhibitors or monoamine oxidase-B inhibitors, anti …
MANAGEMENT: Treatment of manifestations: PINK1 type of young-onset Parkinson disease usually responds well to L-dopa and/or other dopamine a …
Residues of chlorpyrifos in the environment induce resistance in Aedes albopictus by affecting its olfactory system and neurotoxicity.
Chen Y, Zhang C, Li W, Lan R, Chen R, Hu J, Yang C, Wang P, Tang B, Wang S. Chen Y, et al. Sci Total Environ. 2024 Apr 20;930:172425. doi: 10.1016/j.scitotenv.2024.172425. Online ahead of print. Sci Total Environ. 2024. PMID: 38643874
We assessed Ca(2+)-Mg(2+)-ATP levels, choline acetyltransferase (ChAT), Monoamine oxidase (MAO), odorant-binding proteins (OBPs), and olfactory receptor (OR7) gene expression in Ae. albopictus using various assays including Y-shaped tube experiments and DanioVision …
We assessed Ca(2+)-Mg(2+)-ATP levels, choline acetyltransferase (ChAT), Monoamine oxidase (MAO), odorant-binding proteins (OBP …
Lycium barbarum polysaccharides attenuate nonylphenol and octylphenol-induced oxidative stress and neurotransmitter disorders in PC-12 cells.
Xu L, Liu H, Rang Y, Zhou L, Wang X, Li Y, Liu C. Xu L, et al. Toxicology. 2024 Apr 18:153808. doi: 10.1016/j.tox.2024.153808. Online ahead of print. Toxicology. 2024. PMID: 38642822
Additionally, they activated the p38 protein kinase (p38) and suppressed the expression of silent information regulation type 1 (SIRT1), monoamine oxidase A (MAOA), phosphorylated cyclic-AMP response binding protein (p-CREB), brain-derived neurotrophic factor (BDNF) …
Additionally, they activated the p38 protein kinase (p38) and suppressed the expression of silent information regulation type 1 (SIRT1), …
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