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Transcutaneous ultrasound-mediated gene delivery into canine livers achieves therapeutic levels of factor VIII expression.
Blood Adv. 2022 Jun 28;6(12):3557-3568. doi: 10.1182/bloodadvances.2021006016.
Blood Adv. 2022.
PMID: 35427415
Free PMC article.
Ultrasound-mediated gene delivery specifically targets liver sinusoidal endothelial cells for sustained FVIII expression in hemophilia A mice.
Lawton SM, Manson MA, Fan MN, Chao TY, Chen CY, Kim P, Campbell C, Cai X, Vander Kooi A, Miao CH.
Lawton SM, et al. Among authors: manson ma.
Mol Ther. 2024 Apr 3;32(4):969-981. doi: 10.1016/j.ymthe.2024.02.010. Epub 2024 Feb 9.
Mol Ther. 2024.
PMID: 38341614
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Extracellular matrix dysfunction in Sorsby patient-derived retinal pigment epithelium.
Engel AL, Wang Y, Khuu TH, Worrall E, Manson MA, Lim RR, Knight K, Yanagida A, Qi JH, Ramakrishnan A, Weleber RG, Klein ML, Wilson DJ, Anand-Apte B, Hurley JB, Du J, Chao JR.
Engel AL, et al. Among authors: manson ma.
Exp Eye Res. 2022 Feb;215:108899. doi: 10.1016/j.exer.2021.108899. Epub 2021 Dec 17.
Exp Eye Res. 2022.
PMID: 34929159
Free PMC article.
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Human retinal pigment epithelial cells prefer proline as a nutrient and transport metabolic intermediates to the retinal side.
Chao JR, Knight K, Engel AL, Jankowski C, Wang Y, Manson MA, Gu H, Djukovic D, Raftery D, Hurley JB, Du J.
Chao JR, et al. Among authors: manson ma.
J Biol Chem. 2017 Aug 4;292(31):12895-12905. doi: 10.1074/jbc.M117.788422. Epub 2017 Jun 14.
J Biol Chem. 2017.
PMID: 28615447
Free PMC article.
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Reductive carboxylation is a major metabolic pathway in the retinal pigment epithelium.
Du J, Yanagida A, Knight K, Engel AL, Vo AH, Jankowski C, Sadilek M, Tran VT, Manson MA, Ramakrishnan A, Hurley JB, Chao JR.
Du J, et al. Among authors: manson ma.
Proc Natl Acad Sci U S A. 2016 Dec 20;113(51):14710-14715. doi: 10.1073/pnas.1604572113. Epub 2016 Dec 1.
Proc Natl Acad Sci U S A. 2016.
PMID: 27911769
Free PMC article.
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