Mano H - Search Results

1

In vivo imaging of CREB phosphorylation in awake-mouse brain.

Ishimoto T, Mano H, Mori H. Ishimoto T, et al. Among authors: mano h. Sci Rep. 2015 Jun 5;5:9757. doi: 10.1038/srep09757. Sci Rep. 2015. PMID: 26044058 Free PMC article.

2

Measuring CREB activation using bioluminescent probes that detect KID-KIX interaction in living cells.

Ishimoto T, Mano H, Ozawa T, Mori H. Ishimoto T, et al. Among authors: mano h. Bioconjug Chem. 2012 May 16;23(5):923-32. doi: 10.1021/bc200491j. Epub 2012 Apr 16. Bioconjug Chem. 2012. PMID: 22506514

3

Discovery of novel adenylyl cyclase inhibitor by cell-based screening.

Mano H, Ishimoto T, Okada T, Toyooka N, Mori H. Mano H, et al. Biol Pharm Bull. 2014;37(10):1689-93. doi: 10.1248/bpb.b14-00283. Biol Pharm Bull. 2014. PMID: 25273392 Free article.

4

Generation of novel genetically modified rats to reveal the molecular mechanisms of vitamin D actions.

Nishikawa M, Yasuda K, Takamatsu M, Abe K, Okamoto K, Horibe K, Mano H, Nakagawa K, Tsugawa N, Hirota Y, Horie T, Hinoi E, Okano T, Ikushiro S, Sakaki T. Nishikawa M, et al. Among authors: mano h. Sci Rep. 2020 Mar 30;10(1):5677. doi: 10.1038/s41598-020-62048-1. Sci Rep. 2020. PMID: 32231239 Free PMC article.

5

Robust osteogenic efficacy of 2α-heteroarylalkyl vitamin D analogue AH-1 in VDR (R270L) hereditary vitamin D-dependent rickets model rats.

Nishikawa M, Murose N, Mano H, Yasuda K, Isogai Y, Kittaka A, Takano M, Ikushiro S, Sakaki T. Nishikawa M, et al. Among authors: mano h. Sci Rep. 2022 Jul 22;12(1):12517. doi: 10.1038/s41598-022-16819-7. Sci Rep. 2022. PMID: 35869242 Free PMC article.

6

Development of Novel Bioluminescent Sensor to Detect and Discriminate between Vitamin D Receptor Agonists and Antagonists in Living Cells.

Mano H, Nishikawa M, Yasuda K, Ikushiro S, Saito N, Takano M, Kittaka A, Sakaki T. Mano H, et al. Bioconjug Chem. 2015 Oct 21;26(10):2038-45. doi: 10.1021/acs.bioconjchem.5b00433. Epub 2015 Sep 18. Bioconjug Chem. 2015. PMID: 26355700

7

Novel biosensor using split-luciferase for detecting vitamin D receptor ligands based on the interaction between vitamin D receptor and coactivator.

Mano H, Takano M, Ikushiro S, Kittaka A, Sakaki T. Mano H, et al. Biochem Biophys Res Commun. 2018 Oct 28;505(2):460-465. doi: 10.1016/j.bbrc.2018.09.122. Epub 2018 Sep 26. Biochem Biophys Res Commun. 2018. PMID: 30268505

8

Mutant p53-Expressing Cells Undergo Necroptosis via Cell Competition with the Neighboring Normal Epithelial Cells.

Watanabe H, Ishibashi K, Mano H, Kitamoto S, Sato N, Hoshiba K, Kato M, Matsuzawa F, Takeuchi Y, Shirai T, Ishikawa S, Morioka Y, Imagawa T, Sakaguchi K, Yonezawa S, Kon S, Fujita Y. Watanabe H, et al. Among authors: mano h. Cell Rep. 2018 Jun 26;23(13):3721-3729. doi: 10.1016/j.celrep.2018.05.081. Cell Rep. 2018. PMID: 29949757 Free article.

9

Elucidation of metabolic pathways of 25-hydroxyvitamin D3 mediated by CYP24A1 and CYP3A using Cyp24a1 knockout rats generated by CRISPR/Cas9 system.

Yasuda K, Nishikawa M, Okamoto K, Horibe K, Mano H, Yamaguchi M, Okon R, Nakagawa K, Tsugawa N, Okano T, Kawagoe F, Kittaka A, Ikushiro S, Sakaki T. Yasuda K, et al. Among authors: mano h. J Biol Chem. 2021 Jan-Jun;296:100668. doi: 10.1016/j.jbc.2021.100668. Epub 2021 Apr 15. J Biol Chem. 2021. PMID: 33865853 Free PMC article.

10

Novel screening system for high-affinity ligand of heredity vitamin D-resistant rickets-associated vitamin D receptor mutant R274L using bioluminescent sensor.

Mano H, Nishikawa M, Yasuda K, Ikushiro S, Saito N, Sawada D, Honzawa S, Takano M, Kittaka A, Sakaki T. Mano H, et al. J Steroid Biochem Mol Biol. 2017 Mar;167:61-66. doi: 10.1016/j.jsbmb.2016.11.008. Epub 2016 Nov 15. J Steroid Biochem Mol Biol. 2017. PMID: 27864003

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