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Bcl-2 family inhibitors sensitize human cancer models to therapy.
Valentini E, Di Martile M, Brignone M, Di Caprio M, Manni I, Chiappa M, Sergio I, Chiacchiarini M, Bazzichetto C, Conciatori F, D'Aguanno S, D'Angelo C, Ragno R, Russillo M, Colotti G, Marchesi F, Bellone ML, Dal Piaz F, Felli MP, Damia G, Del Bufalo D. Valentini E, et al. Among authors: manni i. Cell Death Dis. 2023 Jul 17;14(7):441. doi: 10.1038/s41419-023-05963-1. Cell Death Dis. 2023. PMID: 37460459 Free PMC article.
Bcl-2-like protein-10 increases aggressive features of melanoma cells.
Del Bufalo D, Di Martile M, Valentini E, Manni I, Masi I, D'Amore A, Filippini A, Nicoletti C, Zaccarini M, Cota C, Castro MV, Quezada MJ, Rosanò L, Lopez-Bergami P, D'Aguanno S. Del Bufalo D, et al. Among authors: manni i. Explor Target Antitumor Ther. 2022;3(1):11-26. doi: 10.37349/etat.2022.00068. Epub 2022 Jan 30. Explor Target Antitumor Ther. 2022. PMID: 36046354 Free PMC article.
Predictive Signatures Inform the Effective Repurposing of Decitabine to Treat KRAS-Dependent Pancreatic Ductal Adenocarcinoma.
Mottini C, Tomihara H, Carrella D, Lamolinara A, Iezzi M, Huang JK, Amoreo CA, Buglioni S, Manni I, Robinson FS, Minelli R, Kang Y, Fleming JB, Kim MP, Bristow CA, Trisciuoglio D, Iuliano A, Del Bufalo D, Di Bernardo D, Melisi D, Draetta GF, Ciliberto G, Carugo A, Cardone L. Mottini C, et al. Among authors: manni i. Cancer Res. 2019 Nov 1;79(21):5612-5625. doi: 10.1158/0008-5472.CAN-19-0187. Epub 2019 Sep 5. Cancer Res. 2019. PMID: 31492820
Establishment of stable iPS-derived human neural stem cell lines suitable for cell therapies.
Rosati J, Ferrari D, Altieri F, Tardivo S, Ricciolini C, Fusilli C, Zalfa C, Profico DC, Pinos F, Bernardini L, Torres B, Manni I, Piaggio G, Binda E, Copetti M, Lamorte G, Mazza T, Carella M, Gelati M, Valente EM, Simeone A, Vescovi AL. Rosati J, et al. Among authors: manni i. Cell Death Dis. 2018 Sep 17;9(10):937. doi: 10.1038/s41419-018-0990-2. Cell Death Dis. 2018. PMID: 30224709 Free PMC article.
Computational drugs repositioning identifies inhibitors of oncogenic PI3K/AKT/P70S6K-dependent pathways among FDA-approved compounds.
Carrella D, Manni I, Tumaini B, Dattilo R, Papaccio F, Mutarelli M, Sirci F, Amoreo CA, Mottolese M, Iezzi M, Ciolli L, Aria V, Bosotti R, Isacchi A, Loreni F, Bardelli A, Avvedimento VE, di Bernardo D, Cardone L. Carrella D, et al. Among authors: manni i. Oncotarget. 2016 Sep 13;7(37):58743-58758. doi: 10.18632/oncotarget.11318. Oncotarget. 2016. PMID: 27542212 Free PMC article.
DHA Affects Microtubule Dynamics Through Reduction of Phospho-TCTP Levels and Enhances the Antiproliferative Effect of T-DM1 in Trastuzumab-Resistant HER2-Positive Breast Cancer Cell Lines.
D'Amico S, Krasnowska EK, Manni I, Toietta G, Baldari S, Piaggio G, Ranalli M, Gambacurta A, Vernieri C, Di Giacinto F, Bernassola F, de Braud F, Lucibello M. D'Amico S, et al. Among authors: manni i. Cells. 2020 May 19;9(5):1260. doi: 10.3390/cells9051260. Cells. 2020. PMID: 32438775 Free PMC article.
Pyrvinium Pamoate Induces Death of Triple-Negative Breast Cancer Stem-Like Cells and Reduces Metastases through Effects on Lipid Anabolism.
Dattilo R, Mottini C, Camera E, Lamolinara A, Auslander N, Doglioni G, Muscolini M, Tang W, Planque M, Ercolani C, Buglioni S, Manni I, Trisciuoglio D, Boe A, Grande S, Luciani AM, Iezzi M, Ciliberto G, Ambs S, De Maria R, Fendt SM, Ruppin E, Cardone L. Dattilo R, et al. Among authors: manni i. Cancer Res. 2020 Oct 1;80(19):4087-4102. doi: 10.1158/0008-5472.CAN-19-1184. Epub 2020 Jul 23. Cancer Res. 2020. PMID: 32718996 Free PMC article.
61 results