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3,956 results

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Page 1
Length-independent telomere damage drives post-mitotic cardiomyocyte senescence.
Anderson R, Lagnado A, Maggiorani D, Walaszczyk A, Dookun E, Chapman J, Birch J, Salmonowicz H, Ogrodnik M, Jurk D, Proctor C, Correia-Melo C, Victorelli S, Fielder E, Berlinguer-Palmini R, Owens A, Greaves LC, Kolsky KL, Parini A, Douin-Echinard V, LeBrasseur NK, Arthur HM, Tual-Chalot S, Schafer MJ, Roos CM, Miller JD, Robertson N, Mann J, Adams PD, Tchkonia T, Kirkland JL, Mialet-Perez J, Richardson GD, Passos JF. Anderson R, et al. Among authors: mann j. EMBO J. 2019 Mar 1;38(5):e100492. doi: 10.15252/embj.2018100492. Epub 2019 Feb 8. EMBO J. 2019. PMID: 30737259 Free PMC article.
Chronic inflammation induces telomere dysfunction and accelerates ageing in mice.
Jurk D, Wilson C, Passos JF, Oakley F, Correia-Melo C, Greaves L, Saretzki G, Fox C, Lawless C, Anderson R, Hewitt G, Pender SL, Fullard N, Nelson G, Mann J, van de Sluis B, Mann DA, von Zglinicki T. Jurk D, et al. Among authors: mann j, mann da. Nat Commun. 2014 Jun 24;2:4172. doi: 10.1038/ncomms5172. Nat Commun. 2014. PMID: 24960204 Free PMC article.
NFκB1 is a suppressor of neutrophil-driven hepatocellular carcinoma.
Wilson CL, Jurk D, Fullard N, Banks P, Page A, Luli S, Elsharkawy AM, Gieling RG, Chakraborty JB, Fox C, Richardson C, Callaghan K, Blair GE, Fox N, Lagnado A, Passos JF, Moore AJ, Smith GR, Tiniakos DG, Mann J, Oakley F, Mann DA. Wilson CL, et al. Among authors: mann j, mann da. Nat Commun. 2015 Apr 16;6:6818. doi: 10.1038/ncomms7818. Nat Commun. 2015. PMID: 25879839 Free PMC article.
Rapamycin improves healthspan but not inflammaging in nfκb1-/- mice.
Correia-Melo C, Birch J, Fielder E, Rahmatika D, Taylor J, Chapman J, Lagnado A, Carroll BM, Miwa S, Richardson G, Jurk D, Oakley F, Mann J, Mann DA, Korolchuk VI, Passos JF. Correia-Melo C, et al. Among authors: mann j, mann da. Aging Cell. 2019 Feb;18(1):e12882. doi: 10.1111/acel.12882. Epub 2018 Nov 23. Aging Cell. 2019. PMID: 30468013 Free PMC article.
A Bioreactor Technology for Modeling Fibrosis in Human and Rodent Precision-Cut Liver Slices.
Paish HL, Reed LH, Brown H, Bryan MC, Govaere O, Leslie J, Barksby BS, Garcia Macia M, Watson A, Xu X, Zaki MYW, Greaves L, Whitehall J, French J, White SA, Manas DM, Robinson SM, Spoletini G, Griffiths C, Mann DA, Borthwick LA, Drinnan MJ, Mann J, Oakley F. Paish HL, et al. Among authors: mann da, mann j. Hepatology. 2019 Oct;70(4):1377-1391. doi: 10.1002/hep.30651. Epub 2019 May 28. Hepatology. 2019. PMID: 30963615 Free PMC article.
The NF-κB subunit c-Rel stimulates cardiac hypertrophy and fibrosis.
Gaspar-Pereira S, Fullard N, Townsend PA, Banks PS, Ellis EL, Fox C, Maxwell AG, Murphy LB, Kirk A, Bauer R, Caamaño JH, Figg N, Foo RS, Mann J, Mann DA, Oakley F. Gaspar-Pereira S, et al. Among authors: mann j, mann da. Am J Pathol. 2012 Mar;180(3):929-939. doi: 10.1016/j.ajpath.2011.11.007. Epub 2011 Dec 30. Am J Pathol. 2012. PMID: 22210479 Free PMC article.
Epigenetic regulation of wound healing and fibrosis.
Mann J, Mann DA. Mann J, et al. Among authors: mann da. Curr Opin Rheumatol. 2013 Jan;25(1):101-7. doi: 10.1097/BOR.0b013e32835b13e1. Curr Opin Rheumatol. 2013. PMID: 23114590 Review.
Corrigendum: NFκB1 is a suppressor of neutrophil-driven hepatocellular carcinoma.
Wilson CL, Jurk D, Fullard N, Banks P, Page A, Luli S, Elsharkawy AM, Gieling RG, Bagchi Chakraborty J, Fox C, Richardson C, Callaghan K, Blair GE, Fox N, Lagnado A, Passos JF, Moore AJ, Smith GR, Tiniakos DG, Mann J, Oakley F, Mann DA. Wilson CL, et al. Among authors: mann j, mann da. Nat Commun. 2015 Sep 21;6:8411. doi: 10.1038/ncomms9411. Nat Commun. 2015. PMID: 26387912 Free PMC article. No abstract available.
3,956 results