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Use-case scenarios for an anti-Cryptosporidium therapeutic.
Ashigbie PG, Shepherd S, Steiner KL, Amadi B, Aziz N, Manjunatha UH, Spector JM, Diagana TT, Kelly P. Ashigbie PG, et al. Among authors: manjunatha uh. PLoS Negl Trop Dis. 2021 Mar 11;15(3):e0009057. doi: 10.1371/journal.pntd.0009057. eCollection 2021 Mar. PLoS Negl Trop Dis. 2021. PMID: 33705395 Free PMC article. Review.
Indolcarboxamide is a preclinical candidate for treating multidrug-resistant tuberculosis.
Rao SP, Lakshminarayana SB, Kondreddi RR, Herve M, Camacho LR, Bifani P, Kalapala SK, Jiricek J, Ma NL, Tan BH, Ng SH, Nanjundappa M, Ravindran S, Seah PG, Thayalan P, Lim SH, Lee BH, Goh A, Barnes WS, Chen Z, Gagaring K, Chatterjee AK, Pethe K, Kuhen K, Walker J, Feng G, Babu S, Zhang L, Blasco F, Beer D, Weaver M, Dartois V, Glynne R, Dick T, Smith PW, Diagana TT, Manjunatha UH. Rao SP, et al. Among authors: manjunatha uh. Sci Transl Med. 2013 Dec 4;5(214):214ra168. doi: 10.1126/scitranslmed.3007355. Sci Transl Med. 2013. PMID: 24307692
A Cryptosporidium PI(4)K inhibitor is a drug candidate for cryptosporidiosis.
Manjunatha UH, Vinayak S, Zambriski JA, Chao AT, Sy T, Noble CG, Bonamy GMC, Kondreddi RR, Zou B, Gedeck P, Brooks CF, Herbert GT, Sateriale A, Tandel J, Noh S, Lakshminarayana SB, Lim SH, Goodman LB, Bodenreider C, Feng G, Zhang L, Blasco F, Wagner J, Leong FJ, Striepen B, Diagana TT. Manjunatha UH, et al. Nature. 2017 Jun 15;546(7658):376-380. doi: 10.1038/nature22337. Epub 2017 May 31. Nature. 2017. PMID: 28562588 Free PMC article.
Innovations in Addressing Pediatric Diarrhea in Low Resource Settings.
Jumani RS, Spector JM, Izadnegahdar R, Kelly P, Diagana TT, Manjunatha UH. Jumani RS, et al. Among authors: manjunatha uh. ACS Infect Dis. 2020 Jan 10;6(1):14-24. doi: 10.1021/acsinfecdis.9b00315. Epub 2019 Oct 29. ACS Infect Dis. 2020. PMID: 31612701
Opportunities and Challenges in Developing a Cryptosporidium Controlled Human Infection Model for Testing Antiparasitic Agents.
Jumani RS, Blais J, Tillmann HC, Segal F, Wetty D, Ostermeier C, Nuber N, Lakshman J, Aziz N, Chandra R, Chen WH, Chappell CL, Diagana TT, Manjunatha UH. Jumani RS, et al. Among authors: manjunatha uh. ACS Infect Dis. 2021 May 14;7(5):959-968. doi: 10.1021/acsinfecdis.1c00057. Epub 2021 Apr 6. ACS Infect Dis. 2021. PMID: 33822577 Free PMC article.
48 results