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DIAPH1 mediates progression of atherosclerosis and regulates hepatic lipid metabolism in mice.
Senatus L, Egaña-Gorroño L, López-Díez R, Bergaya S, Aranda JF, Amengual J, Arivazhagan L, Manigrasso MB, Yepuri G, Nimma R, Mangar KN, Bernadin R, Zhou B, Gugger PF, Li H, Friedman RA, Theise ND, Shekhtman A, Fisher EA, Ramasamy R, Schmidt AM. Senatus L, et al. Among authors: manigrasso mb. Commun Biol. 2023 Mar 17;6(1):280. doi: 10.1038/s42003-023-04643-2. Commun Biol. 2023. PMID: 36932214 Free PMC article.
Pharmacological antagonism of receptor for advanced glycation end products signaling promotes thermogenesis, healthful body mass and composition, and metabolism in mice.
Wilson RA, Arivazhagan L, Ruiz HH, Zhou B, Qian K, Manigrasso MB, Bernadin R, Mangar K, Shekhtman A, Li H, Ramasamy R, Schmidt AM. Wilson RA, et al. Among authors: manigrasso mb. Obesity (Silver Spring). 2023 Jul;31(7):1825-1843. doi: 10.1002/oby.23774. Epub 2023 May 25. Obesity (Silver Spring). 2023. PMID: 37231626
Soluble Receptor for Advanced Glycation End Products (sRAGE) Isoforms Predict Changes in Resting Energy Expenditure in Adults with Obesity during Weight Loss.
Popp CJ, Zhou B, Manigrasso MB, Li H, Curran M, Hu L, St-Jules DE, Alemán JO, Vanegas SM, Jay M, Bergman M, Segal E, Sevick MA, Schmidt AM. Popp CJ, et al. Among authors: manigrasso mb. Curr Dev Nutr. 2022 Mar 29;6(5):nzac046. doi: 10.1093/cdn/nzac046. eCollection 2022 May. Curr Dev Nutr. 2022. PMID: 35542387 Free PMC article.
Small-molecule antagonism of the interaction of the RAGE cytoplasmic domain with DIAPH1 reduces diabetic complications in mice.
Manigrasso MB, Rabbani P, Egaña-Gorroño L, Quadri N, Frye L, Zhou B, Reverdatto S, Ramirez LS, Dansereau S, Pan J, Li H, D'Agati VD, Ramasamy R, DeVita RJ, Shekhtman A, Schmidt AM. Manigrasso MB, et al. Sci Transl Med. 2021 Nov 24;13(621):eabf7084. doi: 10.1126/scitranslmed.abf7084. Epub 2021 Nov 24. Sci Transl Med. 2021. PMID: 34818060 Free PMC article.
Inflammation Meets Metabolism: Roles for the Receptor for Advanced Glycation End Products Axis in Cardiovascular Disease.
Senatus L, MacLean M, Arivazhagan L, Egaña-Gorroño L, López-Díez R, Manigrasso MB, Ruiz HH, Vasquez C, Wilson R, Shekhtman A, Gugger PF, Ramasamy R, Schmidt AM. Senatus L, et al. Among authors: manigrasso mb. Immunometabolism. 2021;3(3):e210024. doi: 10.20900/immunometab20210024. Epub 2021 Jun 2. Immunometabolism. 2021. PMID: 34178389 Free PMC article.
26 results