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HDACs Regulate miR-133a Expression in Pressure Overload-Induced Cardiac Fibrosis.
Renaud L, Harris LG, Mani SK, Kasiganesan H, Chou JC, Baicu CF, Van Laer A, Akerman AW, Stroud RE, Jones JA, Zile MR, Menick DR. Renaud L, et al. Among authors: mani sk. Circ Heart Fail. 2015 Nov;8(6):1094-104. doi: 10.1161/CIRCHEARTFAILURE.114.001781. Epub 2015 Sep 14. Circ Heart Fail. 2015. PMID: 26371176 Free PMC article.
Chronic administration of KB-R7943 induces up-regulation of cardiac NCX1.
Xu L, Kappler CS, Mani SK, Shepherd NR, Renaud L, Snider P, Conway SJ, Menick DR. Xu L, et al. Among authors: mani sk. J Biol Chem. 2009 Oct 2;284(40):27265-72. doi: 10.1074/jbc.M109.022855. Epub 2009 Aug 6. J Biol Chem. 2009. PMID: 19661061 Free PMC article.
Inhibition of class I histone deacetylase activity represses matrix metalloproteinase-2 and -9 expression and preserves LV function postmyocardial infarction.
Mani SK, Kern CB, Kimbrough D, Addy B, Kasiganesan H, Rivers WT, Patel RK, Chou JC, Spinale FG, Mukherjee R, Menick DR. Mani SK, et al. Am J Physiol Heart Circ Physiol. 2015 Jun 1;308(11):H1391-401. doi: 10.1152/ajpheart.00390.2014. Epub 2015 Mar 20. Am J Physiol Heart Circ Physiol. 2015. PMID: 25795711 Free PMC article.
HDAC inhibition helps post-MI healing by modulating macrophage polarization.
Kimbrough D, Wang SH, Wright LH, Mani SK, Kasiganesan H, LaRue AC, Cheng Q, Nadig SN, Atkinson C, Menick DR. Kimbrough D, et al. Among authors: mani sk. J Mol Cell Cardiol. 2018 Jun;119:51-63. doi: 10.1016/j.yjmcc.2018.04.011. Epub 2018 Apr 19. J Mol Cell Cardiol. 2018. PMID: 29680681 Free PMC article.
105 results