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A Novel 7H-[1,2,4]Triazolo[3,4-b]thiadiazine-based Cystic Fibrosis Transmembrane Conductance Regulator Potentiator Directed toward Treatment of Cystic Fibrosis.
Rab A, Yang X, Tracy WF, Hong JS, Joshi D, Manfredi C, Ponnaluri SS, Kolykhalov AA, Qui M, Fu H, Du Y, Davies HML, Sorscher EJ. Rab A, et al. Among authors: manfredi c. ACS Med Chem Lett. 2023 Sep 20;14(10):1338-1343. doi: 10.1021/acsmedchemlett.3c00155. eCollection 2023 Oct 12. ACS Med Chem Lett. 2023. PMID: 37849531 Free PMC article.
Making precision medicine personal for cystic fibrosis.
Manfredi C, Tindall JM, Hong JS, Sorscher EJ. Manfredi C, et al. Science. 2019 Jul 19;365(6450):220-221. doi: 10.1126/science.aaw0553. Science. 2019. PMID: 31320522 Free PMC article. No abstract available.
Type I and Type III Interferons Restrict SARS-CoV-2 Infection of Human Airway Epithelial Cultures.
Vanderheiden A, Ralfs P, Chirkova T, Upadhyay AA, Zimmerman MG, Bedoya S, Aoued H, Tharp GM, Pellegrini KL, Manfredi C, Sorscher E, Mainou B, Lobby JL, Kohlmeier JE, Lowen AC, Shi PY, Menachery VD, Anderson LJ, Grakoui A, Bosinger SE, Suthar MS. Vanderheiden A, et al. Among authors: manfredi c. J Virol. 2020 Sep 15;94(19):e00985-20. doi: 10.1128/JVI.00985-20. Print 2020 Sep 15. J Virol. 2020. PMID: 32699094 Free PMC article.
Marine Natural Products as Leads against SARS-CoV-2 Infection.
Chhetri BK, Tedbury PR, Sweeney-Jones AM, Mani L, Soapi K, Manfredi C, Sorscher E, Sarafianos SG, Kubanek J. Chhetri BK, et al. Among authors: manfredi c. J Nat Prod. 2022 Mar 25;85(3):657-665. doi: 10.1021/acs.jnatprod.2c00015. Epub 2022 Mar 15. J Nat Prod. 2022. PMID: 35290044 Free PMC article.
Engineered tRNAs suppress nonsense mutations in cells and in vivo.
Albers S, Allen EC, Bharti N, Davyt M, Joshi D, Perez-Garcia CG, Santos L, Mukthavaram R, Delgado-Toscano MA, Molina B, Kuakini K, Alayyoubi M, Park KJ, Acharya G, Gonzalez JA, Sagi A, Birket SE, Tearney GJ, Rowe SM, Manfredi C, Hong JS, Tachikawa K, Karmali P, Matsuda D, Sorscher EJ, Chivukula P, Ignatova Z. Albers S, et al. Among authors: manfredi c. Nature. 2023 Jun;618(7966):842-848. doi: 10.1038/s41586-023-06133-1. Epub 2023 May 31. Nature. 2023. PMID: 37258671 Free PMC article.
Mechanisms by which the cystic fibrosis transmembrane conductance regulator may influence SARS-CoV-2 infection and COVID-19 disease severity.
Tedbury PR, Manfredi C, Degenhardt F, Conway J, Horwath MC, McCracken C, Sorscher AJ, Moreau S, Wright C, Edwards C, Brewer J, Guarner J, de Wit E, Williamson BN, Suthar MS, Ong YT, Roback JD, Alter DN, Holter JC, Karlsen TH, Sacchi N, Romero-Gómez M, Invernizzi P, Fernández J, Buti M, Albillos A, Julià A, Valenti L, Asselta R, Banales JM, Bujanda L, de Cid R, Franke A; Severe COVID-19 GWAS group; Sarafianos SG, Hong JS, Sorscher EJ, Ehrhardt A. Tedbury PR, et al. Among authors: manfredi c. FASEB J. 2023 Nov;37(11):e23220. doi: 10.1096/fj.202300077R. FASEB J. 2023. PMID: 37801035
Stably-Inverted Apical-Out Human Upper Airway Organoids for SARS-CoV-2 Infection and Therapeutic Testing.
Lee JH, LeCher JC, Parigoris E, Shinagawa N, Sentosa J, Manfredi C, Goh SL, De R, Tao S, Zandi K, Amblard F, Sorscher EJ, Spence JR, Tirouvanziam R, Schinazi RF, Takayama S. Lee JH, et al. Among authors: manfredi c. bioRxiv [Preprint]. 2024 Jan 4:2024.01.02.573939. doi: 10.1101/2024.01.02.573939. bioRxiv. 2024. PMID: 38260306 Free PMC article. Preprint.
Incidence and management of BPH surgery-related urethral stricture: results from a large U.S. database.
Licari LC, Bologna E, Manfredi C, Franco A, Ditonno F, De Nunzio C, Antonelli A, Simone G, De Sio M, Cindolo L, Olweny EO, Cherullo EE, Leonardo C, Autorino R. Licari LC, et al. Among authors: manfredi c. Prostate Cancer Prostatic Dis. 2024 May 7. doi: 10.1038/s41391-024-00841-z. Online ahead of print. Prostate Cancer Prostatic Dis. 2024. PMID: 38714780
348 results