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Recombinant AAV viral vectors pseudotyped with viral capsids from serotypes 1, 2, and 5 display differential efficiency and cell tropism after delivery to different regions of the central nervous system.
Burger C, Gorbatyuk OS, Velardo MJ, Peden CS, Williams P, Zolotukhin S, Reier PJ, Mandel RJ, Muzyczka N. Burger C, et al. Among authors: mandel rj. Mol Ther. 2004 Aug;10(2):302-17. doi: 10.1016/j.ymthe.2004.05.024. Mol Ther. 2004. PMID: 15294177 Free article.
AAV9: a potential blood-brain barrier buster.
Manfredsson FP, Rising AC, Mandel RJ. Manfredsson FP, et al. Among authors: mandel rj. Mol Ther. 2009 Mar;17(3):403-5. doi: 10.1038/mt.2009.15. Mol Ther. 2009. PMID: 19247366 Free PMC article. No abstract available.
114 results