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TrkB is responsible for EMT transition in malignant pleural effusions derived cultures from adenocarcinoma of the lung.
Ricci A, De Vitis C, Noto A, Fattore L, Mariotta S, Cherubini E, Roscilli G, Liguori G, Scognamiglio G, Rocco G, Botti G, Giarnieri E, Giovagnoli MR, De Toma G, Ciliberto G, Mancini R. Ricci A, et al. Among authors: mancini r. Cell Cycle. 2013 Jun 1;12(11):1696-703. doi: 10.4161/cc.24759. Epub 2013 May 2. Cell Cycle. 2013. PMID: 23656788 Free PMC article.
Activation of an early feedback survival loop involving phospho-ErbB3 is a general response of melanoma cells to RAF/MEK inhibition and is abrogated by anti-ErbB3 antibodies.
Fattore L, Marra E, Pisanu ME, Noto A, de Vitis C, Belleudi F, Aurisicchio L, Mancini R, Torrisi MR, Ascierto PA, Ciliberto G. Fattore L, et al. Among authors: mancini r. J Transl Med. 2013 Jul 27;11:180. doi: 10.1186/1479-5876-11-180. J Transl Med. 2013. PMID: 23890105 Free PMC article.
Lung cancer stem cell lose their stemness default state after exposure to microgravity.
Pisanu ME, Noto A, De Vitis C, Masiello MG, Coluccia P, Proietti S, Giovagnoli MR, Ricci A, Giarnieri E, Cucina A, Ciliberto G, Bizzarri M, Mancini R. Pisanu ME, et al. Among authors: mancini r. Biomed Res Int. 2014;2014:470253. doi: 10.1155/2014/470253. Epub 2014 Sep 7. Biomed Res Int. 2014. PMID: 25276790 Free PMC article.
Combination of antibodies directed against different ErbB3 surface epitopes prevents the establishment of resistance to BRAF/MEK inhibitors in melanoma.
Fattore L, Malpicci D, Marra E, Belleudi F, Noto A, De Vitis C, Pisanu ME, Coluccia P, Camerlingo R, Roscilli G, Ribas A, Di Napoli A, Torrisi MR, Aurisicchio L, Ascierto PA, Mancini R, Ciliberto G. Fattore L, et al. Among authors: mancini r. Oncotarget. 2015 Sep 22;6(28):24823-41. doi: 10.18632/oncotarget.4485. Oncotarget. 2015. PMID: 26208478 Free PMC article.
miR-579-3p controls melanoma progression and resistance to target therapy.
Fattore L, Mancini R, Acunzo M, Romano G, Laganà A, Pisanu ME, Malpicci D, Madonna G, Mallardo D, Capone M, Fulciniti F, Mazzucchelli L, Botti G, Croce CM, Ascierto PA, Ciliberto G. Fattore L, et al. Among authors: mancini r. Proc Natl Acad Sci U S A. 2016 Aug 23;113(34):E5005-13. doi: 10.1073/pnas.1607753113. Epub 2016 Aug 8. Proc Natl Acad Sci U S A. 2016. PMID: 27503895 Free PMC article.
MicroRNAs in melanoma development and resistance to target therapy.
Fattore L, Costantini S, Malpicci D, Ruggiero CF, Ascierto PA, Croce CM, Mancini R, Ciliberto G. Fattore L, et al. Among authors: mancini r. Oncotarget. 2017 Mar 28;8(13):22262-22278. doi: 10.18632/oncotarget.14763. Oncotarget. 2017. PMID: 28118616 Free PMC article. Review.
Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ.
Noto A, De Vitis C, Pisanu ME, Roscilli G, Ricci G, Catizone A, Sorrentino G, Chianese G, Taglialatela-Scafati O, Trisciuoglio D, Del Bufalo D, Di Martile M, Di Napoli A, Ruco L, Costantini S, Jakopin Z, Budillon A, Melino G, Del Sal G, Ciliberto G, Mancini R. Noto A, et al. Among authors: mancini r. Oncogene. 2017 Aug 10;36(32):4573-4584. doi: 10.1038/onc.2017.75. Epub 2017 Apr 3. Oncogene. 2017. PMID: 28368399
804 results