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Trimethylangelicin reduces IL-8 transcription and potentiates CFTR function.
Tamanini A, Borgatti M, Finotti A, Piccagli L, Bezzerri V, Favia M, Guerra L, Lampronti I, Bianchi N, Dall'Acqua F, Vedaldi D, Salvador A, Fabbri E, Mancini I, Nicolis E, Casavola V, Cabrini G, Gambari R. Tamanini A, et al. Among authors: mancini i. Am J Physiol Lung Cell Mol Physiol. 2011 Mar;300(3):L380-90. doi: 10.1152/ajplung.00129.2010. Epub 2010 Dec 10. Am J Physiol Lung Cell Mol Physiol. 2011. PMID: 21148790 Free article.
We previously found that 5-methoxypsoralen reduces Pseudomonas aeruginosa-dependent IL-8 transcription in bronchial epithelial cell lines, with an IC(50) of 10 muM (Nicolis E, Lampronti I, Dechecchi MC, Borgatti M, Tamanini A, Bezzerri V, Bianchi N, Mazzon M, Mancini …
We previously found that 5-methoxypsoralen reduces Pseudomonas aeruginosa-dependent IL-8 transcription in bronchial epithelial cell lines, w …
Induction of IL-6 gene expression in a CF bronchial epithelial cell line by Pseudomonas aeruginosa is dependent on transcription factors belonging to the Sp1 superfamily.
Borgatti M, Bezzerri V, Mancini I, Nicolis E, Dechecchi MC, Lampronti I, Rizzotti P, Cabrini G, Gambari R. Borgatti M, et al. Among authors: mancini i. Biochem Biophys Res Commun. 2007 Jun 15;357(4):977-83. doi: 10.1016/j.bbrc.2007.04.081. Epub 2007 Apr 20. Biochem Biophys Res Commun. 2007. PMID: 17466942
A novel frameshift mutation (+A) at codon 18 of the beta-globin gene associated with high persistence of fetal hemoglobin phenotype and deltabeta-thalassemia.
Feriotto G, Salvatori F, Finotti A, Breveglieri G, Venturi M, Zuccato C, Bianchi N, Borgatti M, Lampronti I, Mancini I, Massei F, Favre C, Gambari R. Feriotto G, et al. Among authors: mancini i. Acta Haematol. 2008;119(1):28-37. doi: 10.1159/000114204. Epub 2008 Jan 30. Acta Haematol. 2008. PMID: 18230963
Pyrogallol, an active compound from the medicinal plant Emblica officinalis, regulates expression of pro-inflammatory genes in bronchial epithelial cells.
Nicolis E, Lampronti I, Dechecchi MC, Borgatti M, Tamanini A, Bianchi N, Bezzerri V, Mancini I, Giri MG, Rizzotti P, Gambari R, Cabrini G. Nicolis E, et al. Among authors: mancini i. Int Immunopharmacol. 2008 Dec 10;8(12):1672-80. doi: 10.1016/j.intimp.2008.08.001. Epub 2008 Aug 27. Int Immunopharmacol. 2008. PMID: 18760383
Docking of molecules identified in bioactive medicinal plants extracts into the p50 NF-kappaB transcription factor: correlation with inhibition of NF-kappaB/DNA interactions and inhibitory effects on IL-8 gene expression.
Piccagli L, Fabbri E, Borgatti M, Bezzerri V, Mancini I, Nicolis E, Dechecchi MC, Lampronti I, Cabrini G, Gambari R. Piccagli L, et al. Among authors: mancini i. BMC Struct Biol. 2008 Sep 3;8:38. doi: 10.1186/1472-6807-8-38. BMC Struct Biol. 2008. PMID: 18768082 Free PMC article.
270 results