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Multiple Antitumor Molecular Mechanisms Are Activated by a Fully Synthetic and Stabilized Pharmaceutical Product Delivering the Active Compound Sulforaphane (SFX-01) in Preclinical Model of Human Glioblastoma.
Colapietro A, Rossetti A, Mancini A, Martellucci S, Ocone G, Pulcini F, Biordi L, Cristiano L, Mattei V, Delle Monache S, Marampon F, Gravina GL, Festuccia C. Colapietro A, et al. Among authors: mancini a. Pharmaceuticals (Basel). 2021 Oct 26;14(11):1082. doi: 10.3390/ph14111082. Pharmaceuticals (Basel). 2021. PMID: 34832864 Free PMC article.
PXD101 potentiates hormonal therapy and prevents the onset of castration-resistant phenotype modulating androgen receptor, HSP90, and CRM1 in preclinical models of prostate cancer.
Gravina GL, Marampon F, Muzi P, Mancini A, Piccolella M, Negri-Cesi P, Motta M, Lenzi A, Di Cesare E, Tombolini V, Jannini EA, Festuccia C. Gravina GL, et al. Among authors: mancini a. Endocr Relat Cancer. 2013 May 21;20(3):321-37. doi: 10.1530/ERC-12-0240. Print 2013 Jun. Endocr Relat Cancer. 2013. PMID: 23507703
Trifluoroibuprofen inhibits α-methylacyl coenzyme A racemase (AMACR/P504S), reduces cancer cell proliferation and inhibits in vivo tumor growth in aggressive prostate cancer models.
Festuccia C, Gravina GL, Mancini A, Muzi P, Cesare ED, Kirk R, Smith M, Hughes S, Gibson R, Lian LY, Ricevuto E, Carnell AJ. Festuccia C, et al. Among authors: mancini a. Anticancer Agents Med Chem. 2014;14(7):1031-41. doi: 10.2174/1871520614666140327152607. Anticancer Agents Med Chem. 2014. PMID: 24712326
Antitumor effects of saffron-derived carotenoids in prostate cancer cell models.
Festuccia C, Mancini A, Gravina GL, Scarsella L, Llorens S, Alonso GL, Tatone C, Di Cesare E, Jannini EA, Lenzi A, D'Alessandro AM, Carmona M. Festuccia C, et al. Among authors: mancini a. Biomed Res Int. 2014;2014:135048. doi: 10.1155/2014/135048. Epub 2014 May 11. Biomed Res Int. 2014. PMID: 24900952 Free PMC article.
XPO1/CRM1-selective inhibitors of nuclear export (SINE) reduce tumor spreading and improve overall survival in preclinical models of prostate cancer (PCa).
Gravina GL, Tortoreto M, Mancini A, Addis A, Di Cesare E, Lenzi A, Landesman Y, McCauley D, Kauffman M, Shacham S, Zaffaroni N, Festuccia C. Gravina GL, et al. Among authors: mancini a. J Hematol Oncol. 2014 Oct 5;7:46. doi: 10.1186/1756-8722-7-46. J Hematol Oncol. 2014. PMID: 25284315 Free PMC article.
1,349 results