Managò A - Search Results

1

Extracellular nicotinate phosphoribosyltransferase binds Toll like receptor 4 and mediates inflammation.

Managò A, Audrito V, Mazzola F, Sorci L, Gaudino F, Gizzi K, Vitale N, Incarnato D, Minazzato G, Ianniello A, Varriale A, D'Auria S, Mengozzi G, Politano G, Oliviero S, Raffaelli N, Deaglio S. Managò A, et al. Nat Commun. 2019 Sep 11;10(1):4116. doi: 10.1038/s41467-019-12055-2. Nat Commun. 2019. PMID: 31511522 Free PMC article.

2

Targeting metabolic reprogramming in metastatic melanoma: The key role of nicotinamide phosphoribosyltransferase (NAMPT).

Audrito V, Managò A, Gaudino F, Deaglio S. Audrito V, et al. Among authors: manago a. Semin Cell Dev Biol. 2020 Feb;98:192-201. doi: 10.1016/j.semcdb.2019.05.001. Epub 2019 May 14. Semin Cell Dev Biol. 2020. PMID: 31059816 Review.

3

Extracellular nicotinamide phosphoribosyltransferase (eNAMPT) is a novel marker for patients with BRAF-mutated metastatic melanoma.

Audrito V, Managò A, Zamporlini F, Rulli E, Gaudino F, Madonna G, D'Atri S, Antonini Cappellini GC, Ascierto PA, Massi D, Raffaelli N, Mandalà M, Deaglio S. Audrito V, et al. Among authors: manago a. Oncotarget. 2018 Apr 10;9(27):18997-19005. doi: 10.18632/oncotarget.24871. eCollection 2018 Apr 10. Oncotarget. 2018. PMID: 29721178 Free PMC article.

4

NAD-Biosynthetic and Consuming Enzymes as Central Players of Metabolic Regulation of Innate and Adaptive Immune Responses in Cancer.

Audrito V, Managò A, Gaudino F, Sorci L, Messana VG, Raffaelli N, Deaglio S. Audrito V, et al. Among authors: manago a. Front Immunol. 2019 Jul 25;10:1720. doi: 10.3389/fimmu.2019.01720. eCollection 2019. Front Immunol. 2019. PMID: 31402913 Free PMC article. Review.

5

Subcellular Characterization of Nicotinamide Adenine Dinucleotide Biosynthesis in Metastatic Melanoma by Using Organelle-Specific Biosensors.

Gaudino F, Manfredonia I, Managò A, Audrito V, Raffaelli N, Vaisitti T, Deaglio S. Gaudino F, et al. Among authors: manago a. Antioxid Redox Signal. 2019 Nov 20;31(15):1150-1165. doi: 10.1089/ars.2019.7799. Antioxid Redox Signal. 2019. PMID: 31456414 Free article.

6

Nicotinamide Phosphoribosyltransferase (NAMPT) as a Therapeutic Target in BRAF-Mutated Metastatic Melanoma.

Audrito V, Managò A, La Vecchia S, Zamporlini F, Vitale N, Baroni G, Cignetto S, Serra S, Bologna C, Stingi A, Arruga F, Vaisitti T, Massi D, Mandalà M, Raffaelli N, Deaglio S. Audrito V, et al. Among authors: manago a. J Natl Cancer Inst. 2018 Mar 1;110(3). doi: 10.1093/jnci/djx198. J Natl Cancer Inst. 2018. PMID: 29309612

7

Pseudomonas aeruginosa pyocyanin induces neutrophil death via mitochondrial reactive oxygen species and mitochondrial acid sphingomyelinase.

Managò A, Becker KA, Carpinteiro A, Wilker B, Soddemann M, Seitz AP, Edwards MJ, Grassmé H, Szabò I, Gulbins E. Managò A, et al. Antioxid Redox Signal. 2015 May 1;22(13):1097-110. doi: 10.1089/ars.2014.5979. Epub 2015 Mar 18. Antioxid Redox Signal. 2015. PMID: 25686490 Free PMC article.

8

Tumor-reducing effect of the clinically used drug clofazimine in a SCID mouse model of pancreatic ductal adenocarcinoma.

Zaccagnino A, Managò A, Leanza L, Gontarewitz A, Linder B, Azzolini M, Biasutto L, Zoratti M, Peruzzo R, Legler K, Trauzold A, Kalthoff H, Szabo I. Zaccagnino A, et al. Among authors: manago a. Oncotarget. 2017 Jun 13;8(24):38276-38293. doi: 10.18632/oncotarget.11299. Oncotarget. 2017. PMID: 27542263 Free PMC article.

9

Intracellular ion channels and cancer.

Leanza L, Biasutto L, Managò A, Gulbins E, Zoratti M, Szabò I. Leanza L, et al. Among authors: manago a. Front Physiol. 2013 Sep 3;4:227. doi: 10.3389/fphys.2013.00227. Front Physiol. 2013. PMID: 24027528 Free PMC article. Review.

10

Direct Pharmacological Targeting of a Mitochondrial Ion Channel Selectively Kills Tumor Cells In Vivo.

Leanza L, Romio M, Becker KA, Azzolini M, Trentin L, Managò A, Venturini E, Zaccagnino A, Mattarei A, Carraretto L, Urbani A, Kadow S, Biasutto L, Martini V, Severin F, Peruzzo R, Trimarco V, Egberts JH, Hauser C, Visentin A, Semenzato G, Kalthoff H, Zoratti M, Gulbins E, Paradisi C, Szabo I. Leanza L, et al. Among authors: manago a. Cancer Cell. 2017 Apr 10;31(4):516-531.e10. doi: 10.1016/j.ccell.2017.03.003. Cancer Cell. 2017. PMID: 28399409 Free article.

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