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Antiviral efficacy of favipiravir against Zika and SARS-CoV-2 viruses in non-human primates.
Marlin R, Desjardins D, Contreras V, Lingas G, Solas C, Roques P, Naninck T, Pascal Q, Behillil S, Maisonnasse P, Lemaitre J, Kahlaoui N, Delache B, Pizzorno A, Nougairede A, Ludot C, Terrier O, Dereuddre-Bosquet N, Relouzat F, Chapon C, Ho Tsong Fang R, van der Werf S, Rosa Calatrava M, Malvy D, de Lamballerie X, Guedj J, Le Grand R. Marlin R, et al. Among authors: malvy d. Nat Commun. 2022 Aug 30;13(1):5108. doi: 10.1038/s41467-022-32565-w. Nat Commun. 2022. PMID: 36042198 Free PMC article.
Experimental Treatment with Favipiravir for Ebola Virus Disease (the JIKI Trial): A Historically Controlled, Single-Arm Proof-of-Concept Trial in Guinea.
Sissoko D, Laouenan C, Folkesson E, M'Lebing AB, Beavogui AH, Baize S, Camara AM, Maes P, Shepherd S, Danel C, Carazo S, Conde MN, Gala JL, Colin G, Savini H, Bore JA, Le Marcis F, Koundouno FR, Petitjean F, Lamah MC, Diederich S, Tounkara A, Poelart G, Berbain E, Dindart JM, Duraffour S, Lefevre A, Leno T, Peyrouset O, Irenge L, Bangoura N, Palich R, Hinzmann J, Kraus A, Barry TS, Berette S, Bongono A, Camara MS, Chanfreau Munoz V, Doumbouya L, Souley Harouna, Kighoma PM, Koundouno FR, Réné Lolamou, Loua CM, Massala V, Moumouni K, Provost C, Samake N, Sekou C, Soumah A, Arnould I, Komano MS, Gustin L, Berutto C, Camara D, Camara FS, Colpaert J, Delamou L, Jansson L, Kourouma E, Loua M, Malme K, Manfrin E, Maomou A, Milinouno A, Ombelet S, Sidiboun AY, Verreckt I, Yombouno P, Bocquin A, Carbonnelle C, Carmoi T, Frange P, Mely S, Nguyen VK, Pannetier D, Taburet AM, Treluyer JM, Kolie J, Moh R, Gonzalez MC, Kuisma E, Liedigk B, Ngabo D, Rudolf M, Thom R, Kerber R, Gabriel M, Di Caro A, Wölfel R, Badir J, Bentahir M, Deccache Y, Dumont C, Durant JF, El Bakkouri K, Gasasira Uwamahoro M, Smits B, Toufik N, Van Cauwenberghe S, Ezzedine K, D'Ortenzio E, Pizarro L, Etienne A, Guedj… See abstract for full author list ➔ Sissoko D, et al. Among authors: d ortenzio e, malvy d. PLoS Med. 2016 Mar 1;13(3):e1001967. doi: 10.1371/journal.pmed.1001967. eCollection 2016 Mar. PLoS Med. 2016. PMID: 26930627 Free PMC article. Clinical Trial.
Favipiravir pharmacokinetics in Ebola-Infected patients of the JIKI trial reveals concentrations lower than targeted.
Nguyen TH, Guedj J, Anglaret X, Laouénan C, Madelain V, Taburet AM, Baize S, Sissoko D, Pastorino B, Rodallec A, Piorkowski G, Carazo S, Conde MN, Gala JL, Bore JA, Carbonnelle C, Jacquot F, Raoul H, Malvy D, de Lamballerie X, Mentré F; JIKI study group. Nguyen TH, et al. Among authors: malvy d. PLoS Negl Trop Dis. 2017 Feb 23;11(2):e0005389. doi: 10.1371/journal.pntd.0005389. eCollection 2017 Feb. PLoS Negl Trop Dis. 2017. PMID: 28231247 Free PMC article. Clinical Trial.
Probable Sexually Transmitted Zika Virus Infection in a Pregnant Woman.
Desclaux A, de Lamballerie X, Leparc-Goffart I, Vilain-Parcé A, Coatleven F, Fleury H, Malvy D. Desclaux A, et al. Among authors: malvy d. N Engl J Med. 2018 Apr 12;378(15):1458-1460. doi: 10.1056/NEJMc1710453. N Engl J Med. 2018. PMID: 29641959 Free article. No abstract available.
First cases of coronavirus disease 2019 (COVID-19) in France: surveillance, investigations and control measures, January 2020.
Bernard Stoecklin S, Rolland P, Silue Y, Mailles A, Campese C, Simondon A, Mechain M, Meurice L, Nguyen M, Bassi C, Yamani E, Behillil S, Ismael S, Nguyen D, Malvy D, Lescure FX, Georges S, Lazarus C, Tabaï A, Stempfelet M, Enouf V, Coignard B, Levy-Bruhl D; Investigation team. Bernard Stoecklin S, et al. Among authors: malvy d. Euro Surveill. 2020 Feb;25(6):2000094. doi: 10.2807/1560-7917.ES.2020.25.6.2000094. Euro Surveill. 2020. PMID: 32070465 Free PMC article.
Modeling Favipiravir Antiviral Efficacy Against Emerging Viruses: From Animal Studies to Clinical Trials.
Madelain V, Mentré F, Baize S, Anglaret X, Laouénan C, Oestereich L, Nguyen THT, Malvy D, Piorkowski G, Graw F, Günther S, Raoul H, de Lamballerie X, Guedj J. Madelain V, et al. Among authors: malvy d. CPT Pharmacometrics Syst Pharmacol. 2020 May;9(5):258-271. doi: 10.1002/psp4.12510. Epub 2020 Apr 28. CPT Pharmacometrics Syst Pharmacol. 2020. PMID: 32198838 Free PMC article. Review.
Clinical and virological data of the first cases of COVID-19 in Europe: a case series.
Lescure FX, Bouadma L, Nguyen D, Parisey M, Wicky PH, Behillil S, Gaymard A, Bouscambert-Duchamp M, Donati F, Le Hingrat Q, Enouf V, Houhou-Fidouh N, Valette M, Mailles A, Lucet JC, Mentre F, Duval X, Descamps D, Malvy D, Timsit JF, Lina B, van-der-Werf S, Yazdanpanah Y. Lescure FX, et al. Among authors: malvy d. Lancet Infect Dis. 2020 Jun;20(6):697-706. doi: 10.1016/S1473-3099(20)30200-0. Epub 2020 Mar 27. Lancet Infect Dis. 2020. PMID: 32224310 Free PMC article.
Dose Rationale for Favipiravir Use in Patients Infected With SARS-CoV-2.
Eloy P, Solas C, Touret F, Mentré F, Malvy D, de Lamballerie X, Guedj J. Eloy P, et al. Among authors: malvy d. Clin Pharmacol Ther. 2020 Aug;108(2):188. doi: 10.1002/cpt.1877. Epub 2020 May 21. Clin Pharmacol Ther. 2020. PMID: 32350860 No abstract available.
Timing of antiviral treatment initiation is critical to reduce SARS-CoV-2 viral load.
Gonçalves A, Bertrand J, Ke R, Comets E, de Lamballerie X, Malvy D, Pizzorno A, Terrier O, Calatrava MR, Mentré F, Smith P, Perelson AS, Guedj J. Gonçalves A, et al. Among authors: malvy d. medRxiv [Preprint]. 2020 Jun 21:2020.04.04.20047886. doi: 10.1101/2020.04.04.20047886. medRxiv. 2020. PMID: 32511641 Free PMC article. Updated. Preprint.
Timing of Antiviral Treatment Initiation is Critical to Reduce SARS-CoV-2 Viral Load.
Gonçalves A, Bertrand J, Ke R, Comets E, de Lamballerie X, Malvy D, Pizzorno A, Terrier O, Rosa Calatrava M, Mentré F, Smith P, Perelson AS, Guedj J. Gonçalves A, et al. Among authors: malvy d. CPT Pharmacometrics Syst Pharmacol. 2020 Sep;9(9):509-514. doi: 10.1002/psp4.12543. Epub 2020 Aug 7. CPT Pharmacometrics Syst Pharmacol. 2020. PMID: 32558354 Free PMC article.
521 results