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ProNGF\NGF imbalance triggers learning and memory deficits, neurodegeneration and spontaneous epileptic-like discharges in transgenic mice.
Tiveron C, Fasulo L, Capsoni S, Malerba F, Marinelli S, Paoletti F, Piccinin S, Scardigli R, Amato G, Brandi R, Capelli P, D'Aguanno S, Florenzano F, La Regina F, Lecci A, Manca A, Meli G, Pistillo L, Berretta N, Nisticò R, Pavone F, Cattaneo A. Tiveron C, et al. Among authors: malerba f. Cell Death Differ. 2013 Aug;20(8):1017-30. doi: 10.1038/cdd.2013.22. Epub 2013 Mar 29. Cell Death Differ. 2013. PMID: 23538417 Free PMC article.
Passive immunotherapy for N-truncated tau ameliorates the cognitive deficits in two mouse Alzheimer's disease models.
Corsetti V, Borreca A, Latina V, Giacovazzo G, Pignataro A, Krashia P, Natale F, Cocco S, Rinaudo M, Malerba F, Florio R, Ciarapica R, Coccurello R, D'Amelio M, Ammassari-Teule M, Grassi C, Calissano P, Amadoro G. Corsetti V, et al. Among authors: malerba f. Brain Commun. 2020 Apr 6;2(1):fcaa039. doi: 10.1093/braincomms/fcaa039. eCollection 2020. Brain Commun. 2020. PMID: 32954296 Free PMC article.
Systemic delivery of a specific antibody targeting the pathological N-terminal truncated tau peptide reduces retinal degeneration in a mouse model of Alzheimer's Disease.
Latina V, Giacovazzo G, Cordella F, Balzamino BO, Micera A, Varano M, Marchetti C, Malerba F, Florio R, Ercole BB, La Regina F, Atlante A, Coccurello R, Di Angelantonio S, Calissano P, Amadoro G. Latina V, et al. Among authors: malerba f. Acta Neuropathol Commun. 2021 Mar 9;9(1):38. doi: 10.1186/s40478-021-01138-1. Acta Neuropathol Commun. 2021. PMID: 33750467 Free PMC article.
Lamotrigine rescues neuronal alterations and prevents seizure-induced memory decline in an Alzheimer's disease mouse model.
Rizzello E, Pimpinella D, Pignataro A, Titta G, Merenda E, Saviana M, Porcheddu GF, Paolantoni C, Malerba F, Giorgi C, Curia G, Middei S, Marchetti C. Rizzello E, et al. Among authors: malerba f. Neurobiol Dis. 2023 Jun 1;181:106106. doi: 10.1016/j.nbd.2023.106106. Epub 2023 Mar 29. Neurobiol Dis. 2023. PMID: 37001613 Free article.
72 results