Malech HL - Search Results

1

Preclinical evaluation for engraftment of CD34⁺ cells gene-edited at the sickle cell disease locus in xenograft mouse and non-human primate models.

Uchida N, Li L, Nassehi T, Drysdale CM, Yapundich M, Gamer J, Haro-Mora JJ, Demirci S, Leonard A, Bonifacino AC, Krouse AE, Linde NS, Allen C, Peshwa MV, De Ravin SS, Donahue RE, Malech HL, Tisdale JF. Uchida N, et al. Among authors: malech hl. Cell Rep Med. 2021 Apr 20;2(4):100247. doi: 10.1016/j.xcrm.2021.100247. eCollection 2021 Apr 20. Cell Rep Med. 2021. PMID: 33948577 Free PMC article.

2

Nonmyeloablative conditioning followed by transplantation of genetically modified HLA-matched peripheral blood progenitor cells for hematologic malignancies in patients with acquired immunodeficiency syndrome.

Kang EM, de Witte M, Malech H, Morgan RA, Phang S, Carter C, Leitman SF, Childs R, Barrett AJ, Little R, Tisdale JF. Kang EM, et al. Blood. 2002 Jan 15;99(2):698-701. doi: 10.1182/blood.v99.2.698. Blood. 2002. PMID: 11781257 Free article.

3

Gene therapy-based treatment for HIV-positive patients with malignancies.

Kang EM, De Witte M, Malech H, Morgan RA, Carter C, Leitman SF, Childs R, Barrett AJ, Little R, Tisdale JF. Kang EM, et al. J Hematother Stem Cell Res. 2002 Oct;11(5):809-16. doi: 10.1089/152581602760404612. J Hematother Stem Cell Res. 2002. PMID: 12427287

4

Nuclear-localizing O6-benzylguanine-resistant GFP-MGMT fusion protein as a novel in vivo selection marker.

Choi U, DeRavin SS, Yamashita K, Whiting-Theobald N, Linton GF, Loktionova NA, Pegg AE, Malech HL. Choi U, et al. Among authors: malech hl. Exp Hematol. 2004 Aug;32(8):709-19. doi: 10.1016/j.exphem.2004.05.022. Exp Hematol. 2004. PMID: 15308322 Free article.

5

Cloning and functional analysis of the rhesus macaque ABCG2 gene. Forced expression confers an SP phenotype among hematopoietic stem cell progeny in vivo.

Ueda T, Brenner S, Malech HL, Langemeijer SM, Perl S, Kirby M, Phang OA, Krouse AE, Donahue RE, Kang EM, Tisdale JF. Ueda T, et al. Among authors: malech hl. J Biol Chem. 2005 Jan 14;280(2):991-8. doi: 10.1074/jbc.M409796200. Epub 2004 Oct 30. J Biol Chem. 2005. PMID: 15516692 Free article.

6

Sarcoidosis in chronic granulomatous disease.

De Ravin SS, Naumann N, Robinson MR, Barron KS, Kleiner DE, Ulrick J, Friend J, Anderson VL, Darnell D, Kang EM, Malech HL. De Ravin SS, et al. Among authors: malech hl. Pediatrics. 2006 Mar;117(3):e590-5. doi: 10.1542/peds.2005-1349. Epub 2006 Feb 1. Pediatrics. 2006. PMID: 16452321

7

WHIM syndrome myelokathexis reproduced in the NOD/SCID mouse xenotransplant model engrafted with healthy human stem cells transduced with C-terminus-truncated CXCR4.

Kawai T, Choi U, Cardwell L, DeRavin SS, Naumann N, Whiting-Theobald NL, Linton GF, Moon J, Murphy PM, Malech HL. Kawai T, et al. Among authors: malech hl. Blood. 2007 Jan 1;109(1):78-84. doi: 10.1182/blood-2006-05-025296. Epub 2006 Aug 31. Blood. 2007. PMID: 16946301 Free PMC article.

8

Gene therapy improves immune function in preadolescents with X-linked severe combined immunodeficiency.

Chinen J, Davis J, De Ravin SS, Hay BN, Hsu AP, Linton GF, Naumann N, Nomicos EY, Silvin C, Ulrick J, Whiting-Theobald NL, Malech HL, Puck JM. Chinen J, et al. Among authors: malech hl. Blood. 2007 Jul 1;110(1):67-73. doi: 10.1182/blood-2006-11-058933. Epub 2007 Mar 16. Blood. 2007. PMID: 17369490 Free PMC article. Clinical Trial.

9

Simian immunodeficiency virus lentivector corrects human X-linked chronic granulomatous disease in the NOD/SCID mouse xenograft.

Naumann N, De Ravin SS, Choi U, Moayeri M, Whiting-Theobald N, Linton GF, Ikeda Y, Malech HL. Naumann N, et al. Among authors: malech hl. Gene Ther. 2007 Nov;14(21):1513-24. doi: 10.1038/sj.gt.3303010. Epub 2007 Aug 30. Gene Ther. 2007. PMID: 17728796 Free PMC article.

10

Donor demographic and laboratory predictors of allogeneic peripheral blood stem cell mobilization in an ethnically diverse population.

Vasu S, Leitman SF, Tisdale JF, Hsieh MM, Childs RW, Barrett AJ, Fowler DH, Bishop MR, Kang EM, Malech HL, Dunbar CE, Khuu HM, Wesley R, Yau YY, Bolan CD. Vasu S, et al. Among authors: malech hl. Blood. 2008 Sep 1;112(5):2092-100. doi: 10.1182/blood-2008-03-143677. Epub 2008 Jun 3. Blood. 2008. PMID: 18523146 Free PMC article.

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