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A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation resulting in pro-metastatic NF-κB signaling.
Altea-Manzano P, Doglioni G, Liu Y, Cuadros AM, Nolan E, Fernández-García J, Wu Q, Planque M, Laue KJ, Cidre-Aranaz F, Liu XZ, Marin-Bejar O, Van Elsen J, Vermeire I, Broekaert D, Demeyer S, Spotbeen X, Idkowiak J, Montagne A, Demicco M, Alkan HF, Rabas N, Riera-Domingo C, Richard F, Geukens T, De Schepper M, Leduc S, Hatse S, Lambrechts Y, Kay EJ, Lilla S, Alekseenko A, Geldhof V, Boeckx B, de la Calle Arregui C, Floris G, Swinnen JV, Marine JC, Lambrechts D, Pelechano V, Mazzone M, Zanivan S, Cools J, Wildiers H, Baud V, Grünewald TGP, Ben-David U, Desmedt C, Malanchi I, Fendt SM. Altea-Manzano P, et al. Among authors: malanchi i. Nat Cancer. 2023 Mar;4(3):344-364. doi: 10.1038/s43018-023-00513-2. Epub 2023 Feb 2. Nat Cancer. 2023. PMID: 36732635 Free PMC article.
Metastatic-niche labelling reveals parenchymal cells with stem features.
Ombrato L, Nolan E, Kurelac I, Mavousian A, Bridgeman VL, Heinze I, Chakravarty P, Horswell S, Gonzalez-Gualda E, Matacchione G, Weston A, Kirkpatrick J, Husain E, Speirs V, Collinson L, Ori A, Lee JH, Malanchi I. Ombrato L, et al. Among authors: malanchi i. Nature. 2019 Aug;572(7771):603-608. doi: 10.1038/s41586-019-1487-6. Epub 2019 Aug 28. Nature. 2019. PMID: 31462798 Free PMC article.
Generation of neighbor-labeling cells to study intercellular interactions in vivo.
Ombrato L, Nolan E, Passaro D, Kurelac I, Bridgeman VL, Waclawiczek A, Duarte D, Lo Celso C, Bonnet D, Malanchi I. Ombrato L, et al. Among authors: malanchi i. Nat Protoc. 2021 Feb;16(2):872-892. doi: 10.1038/s41596-020-00438-5. Epub 2020 Dec 11. Nat Protoc. 2021. PMID: 33311715 Free PMC article.
Mechanisms of Organ-Specific Metastasis of Breast Cancer.
Nolan E, Kang Y, Malanchi I. Nolan E, et al. Among authors: malanchi i. Cold Spring Harb Perspect Med. 2023 Nov 1;13(11):a041326. doi: 10.1101/cshperspect.a041326. Cold Spring Harb Perspect Med. 2023. PMID: 36987584 Review.
50 results