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Blocking Dectin-1 prevents colorectal tumorigenesis by suppressing prostaglandin E2 production in myeloid-derived suppressor cells and enhancing IL-22 binding protein expression.
Nat Commun. 2023 Mar 17;14(1):1493. doi: 10.1038/s41467-023-37229-x.
Nat Commun. 2023.
PMID: 36932082
Free PMC article.
Blocking DCIR mitigates colitis and prevents colorectal tumors by enhancing the GM-CSF-STAT5 pathway.
Sun H, Tang C, Chung SH, Ye XQ, Makusheva Y, Han W, Kubo M, Shichino S, Ueha S, Matsushima K, Ikeo K, Asano M, Iwakura Y.
Sun H, et al. Among authors: makusheva y.
Cell Rep. 2022 Aug 2;40(5):111158. doi: 10.1016/j.celrep.2022.111158.
Cell Rep. 2022.
PMID: 35926458
Free article.
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The C-type lectin receptor Clec1A plays an important role in the development of experimental autoimmune encephalomyelitis by enhancing antigen presenting ability of dendritic cells and inducing inflammatory cytokine IL-17.
Makusheva Y, Chung SH, Akitsu A, Maeda N, Maruhashi T, Ye XQ, Kaifu T, Saijo S, Sun H, Han W, Tang C, Iwakura Y.
Makusheva Y, et al.
Exp Anim. 2022 Aug 5;71(3):288-304. doi: 10.1538/expanim.21-0191. Epub 2022 May 8.
Exp Anim. 2022.
PMID: 35135958
Free PMC article.
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Myeloid C-type lectin receptors in skin/mucoepithelial diseases and tumors.
Tang C, Makusheva Y, Sun H, Han W, Iwakura Y.
Tang C, et al. Among authors: makusheva y.
J Leukoc Biol. 2019 Oct;106(4):903-917. doi: 10.1002/JLB.2RI0119-031R. Epub 2019 Apr 9.
J Leukoc Biol. 2019.
PMID: 30964564
Free PMC article.
Review.
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