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Cryo-EM structure of pleconaril-resistant rhinovirus-B5 complexed to the antiviral OBR-5-340 reveals unexpected binding site.
Wald J, Pasin M, Richter M, Walther C, Mathai N, Kirchmair J, Makarov VA, Goessweiner-Mohr N, Marlovits TC, Zanella I, Real-Hohn A, Verdaguer N, Blaas D, Schmidtke M. Wald J, et al. Among authors: makarov va. Proc Natl Acad Sci U S A. 2019 Sep 17;116(38):19109-19115. doi: 10.1073/pnas.1904732116. Epub 2019 Aug 28. Proc Natl Acad Sci U S A. 2019. PMID: 31462495 Free PMC article.
Susceptibility of coxsackievirus B3 laboratory strains and clinical isolates to the capsid function inhibitor pleconaril: antiviral studies with virus chimeras demonstrate the crucial role of amino acid 1092 in treatment.
Schmidtke M, Hammerschmidt E, Schüler S, Zell R, Birch-Hirschfeld E, Makarov VA, Riabova OB, Wutzler P. Schmidtke M, et al. Among authors: makarov va. J Antimicrob Chemother. 2005 Oct;56(4):648-56. doi: 10.1093/jac/dki263. Epub 2005 Sep 8. J Antimicrob Chemother. 2005. PMID: 16150864
Per aspera ad astra: application of Simplex QSAR approach in antiviral research.
Muratov EN, Artemenko AG, Varlamova EV, Polischuk PG, Lozitsky VP, Fedchuk AS, Lozitska RL, Gridina TL, Koroleva LS, Sil'nikov VN, Galabov AS, Makarov VA, Riabova OB, Wutzler P, Schmidtke M, Kuz'min VE. Muratov EN, et al. Among authors: makarov va. Future Med Chem. 2010 Jul;2(7):1205-26. doi: 10.4155/fmc.10.194. Future Med Chem. 2010. PMID: 21426164 Review.
306 results