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Affinity-matured HLA class II dimers for robust staining of antigen-specific CD4+ T cells.
Sugata K, Matsunaga Y, Yamashita Y, Nakatsugawa M, Guo T, Halabelian L, Ohashi Y, Saso K, Rahman MA, Anczurowski M, Wang CH, Murata K, Saijo H, Kagoya Y, Ly D, Burt BD, Butler MO, Mak TW, Hirano N. Sugata K, et al. Among authors: mak tw. Nat Biotechnol. 2021 Aug;39(8):958-967. doi: 10.1038/s41587-021-00836-4. Epub 2021 Mar 1. Nat Biotechnol. 2021. PMID: 33649568
Blood pressure regulation by CD4+ lymphocytes expressing choline acetyltransferase.
Olofsson PS, Steinberg BE, Sobbi R, Cox MA, Ahmed MN, Oswald M, Szekeres F, Hanes WM, Introini A, Liu SF, Holodick NE, Rothstein TL, Lövdahl C, Chavan SS, Yang H, Pavlov VA, Broliden K, Andersson U, Diamond B, Miller EJ, Arner A, Gregersen PK, Backx PH, Mak TW, Tracey KJ. Olofsson PS, et al. Among authors: mak tw. Nat Biotechnol. 2016 Oct;34(10):1066-1071. doi: 10.1038/nbt.3663. Epub 2016 Sep 12. Nat Biotechnol. 2016. PMID: 27617738 Free PMC article.
Landscape mapping of shared antigenic epitopes and their cognate TCRs of tumor-infiltrating T lymphocytes in melanoma.
Murata K, Nakatsugawa M, Rahman MA, Nguyen LT, Millar DG, Mulder DT, Sugata K, Saijo H, Matsunaga Y, Kagoya Y, Guo T, Anczurowski M, Wang CH, Burt BD, Ly D, Saso K, Easson A, Goldstein DP, Reedijk M, Ghazarian D, Pugh TJ, Butler MO, Mak TW, Ohashi PS, Hirano N. Murata K, et al. Among authors: mak tw. Elife. 2020 Apr 21;9:e53244. doi: 10.7554/eLife.53244. Elife. 2020. PMID: 32314731 Free PMC article.
Increase in serum choline levels predicts for improved progression-free survival (PFS) in patients with advanced cancers receiving pembrolizumab.
Watson GA, Sanz-Garcia E, Zhang WJ, Liu ZA, Yang SC, Wang B, Liu S, Kubli S, Berman H, Pfister T, Genta S, Spreafico A, Hansen AR, Bedard PL, Lheureux S, Abdul Razak A, Cescon D, Butler MO, Xu W, Mak TW, Siu LL, Chen E. Watson GA, et al. Among authors: mak tw. J Immunother Cancer. 2022 Jun;10(6):e004378. doi: 10.1136/jitc-2021-004378. J Immunother Cancer. 2022. PMID: 35705312 Free PMC article.
Ex vivo activation of the GCN2 pathway metabolically reprograms T cells, leading to enhanced adoptive cell therapy.
St Paul M, Saibil SD, Kates M, Han S, Lien SC, Laister RC, Hezaveh K, Kloetgen A, Penny S, Guo T, Garcia-Batres C, Smith LK, Chung DC, Elford AR, Sayad A, Pinto D, Mak TW, Hirano N, McGaha T, Ohashi PS. St Paul M, et al. Among authors: mak tw. Cell Rep Med. 2024 Mar 19;5(3):101465. doi: 10.1016/j.xcrm.2024.101465. Epub 2024 Mar 8. Cell Rep Med. 2024. PMID: 38460518 Free PMC article.
CD4 T cells, lymphopenia, and IL-7 in a multistep pathway to autoimmunity.
Calzascia T, Pellegrini M, Lin A, Garza KM, Elford AR, Shahinian A, Ohashi PS, Mak TW. Calzascia T, et al. Among authors: mak tw. Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):2999-3004. doi: 10.1073/pnas.0712135105. Epub 2008 Feb 14. Proc Natl Acad Sci U S A. 2008. PMID: 18287017 Free PMC article.
IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics.
Sasaki M, Knobbe CB, Munger JC, Lind EF, Brenner D, Brüstle A, Harris IS, Holmes R, Wakeham A, Haight J, You-Ten A, Li WY, Schalm S, Su SM, Virtanen C, Reifenberger G, Ohashi PS, Barber DL, Figueroa ME, Melnick A, Zúñiga-Pflücker JC, Mak TW. Sasaki M, et al. Among authors: mak tw. Nature. 2012 Aug 30;488(7413):656-9. doi: 10.1038/nature11323. Nature. 2012. PMID: 22763442 Free PMC article.
ANP32E is a histone chaperone that removes H2A.Z from chromatin.
Obri A, Ouararhni K, Papin C, Diebold ML, Padmanabhan K, Marek M, Stoll I, Roy L, Reilly PT, Mak TW, Dimitrov S, Romier C, Hamiche A. Obri A, et al. Among authors: mak tw. Nature. 2014 Jan 30;505(7485):648-53. doi: 10.1038/nature12922. Epub 2014 Jan 22. Nature. 2014. PMID: 24463511
1,082 results