Major PP - Search Results

1

Overview of phase I studies of intravenous administration of PV701, an oncolytic virus.

Lorence RM, Pecora AL, Major PP, Hotte SJ, Laurie SA, Roberts MS, Groene WS, Bamat MK. Lorence RM, et al. Among authors: major pp. Curr Opin Mol Ther. 2003 Dec;5(6):618-24. Curr Opin Mol Ther. 2003. PMID: 14755888 Review.

2

An optimized clinical regimen for the oncolytic virus PV701.

Hotte SJ, Lorence RM, Hirte HW, Polawski SR, Bamat MK, O'Neil JD, Roberts MS, Groene WS, Major PP. Hotte SJ, et al. Among authors: major pp. Clin Cancer Res. 2007 Feb 1;13(3):977-85. doi: 10.1158/1078-0432.CCR-06-1817. Clin Cancer Res. 2007. PMID: 17289893 Clinical Trial.

3

Tn-MUC1 DC Vaccination of Rhesus Macaques and a Phase I/II Trial in Patients with Nonmetastatic Castrate-Resistant Prostate Cancer.

Scheid E, Major P, Bergeron A, Finn OJ, Salter RD, Eady R, Yassine-Diab B, Favre D, Peretz Y, Landry C, Hotte S, Mukherjee SD, Dekaban GA, Fink C, Foster PJ, Gaudet J, Gariepy J, Sekaly RP, Lacombe L, Fradet Y, Foley R. Scheid E, et al. Cancer Immunol Res. 2016 Oct;4(10):881-892. doi: 10.1158/2326-6066.CIR-15-0189. Epub 2016 Sep 7. Cancer Immunol Res. 2016. PMID: 27604597 Free PMC article. Clinical Trial.

4

A phase II clinical and pharmacokinetic study of intravenous exatecan mesylate (DX-8951f) in patients with untreated metastatic gastric cancer.

Ajani JA, Takimoto C, Becerra CR, Silva A, Baez L, Cohn A, Major P, Kamida M, Feit K, De Jager R. Ajani JA, et al. Invest New Drugs. 2005 Oct;23(5):479-84. doi: 10.1007/s10637-005-2907-z. Invest New Drugs. 2005. PMID: 16133799 Clinical Trial.

5

A phase I dose escalation study of the matrix metalloproteinase inhibitor BAY 12-9566 administered orally in patients with advanced solid tumours.

Hirte H, Goel R, Major P, Seymour L, Huan S, Stewart D, Yau J, Arnold A, Holohan S, Waterfield B, Bates S, Bennett K, Walsh W, Elias I. Hirte H, et al. Ann Oncol. 2000 Dec;11(12):1579-84. doi: 10.1023/a:1008347630465. Ann Oncol. 2000. PMID: 11205466 Free article. Clinical Trial.

6

Combining Vascular Normalization with an Oncolytic Virus Enhances Immunotherapy in a Preclinical Model of Advanced-Stage Ovarian Cancer.

Matuszewska K, Santry LA, van Vloten JP, AuYeung AWK, Major PP, Lawler J, Wootton SK, Bridle BW, Petrik J. Matuszewska K, et al. Among authors: major pp. Clin Cancer Res. 2019 Mar 1;25(5):1624-1638. doi: 10.1158/1078-0432.CCR-18-0220. Epub 2018 Sep 11. Clin Cancer Res. 2019. PMID: 30206160

7

A phase II trial with pharmacodynamic endpoints of the proteasome inhibitor bortezomib in patients with metastatic colorectal cancer.

Mackay H, Hedley D, Major P, Townsley C, Mackenzie M, Vincent M, Degendorfer P, Tsao MS, Nicklee T, Birle D, Wright J, Siu L, Moore M, Oza A. Mackay H, et al. Clin Cancer Res. 2005 Aug 1;11(15):5526-33. doi: 10.1158/1078-0432.CCR-05-0081. Clin Cancer Res. 2005. PMID: 16061869 Clinical Trial.

8

A pharmacodynamic study of the epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 in metastatic colorectal cancer patients.

Daneshmand M, Parolin DA, Hirte HW, Major P, Goss G, Stewart D, Batist G, Miller WH Jr, Matthews S, Seymour L, Lorimer IA. Daneshmand M, et al. Clin Cancer Res. 2003 Jul;9(7):2457-64. Clin Cancer Res. 2003. PMID: 12855618 Clinical Trial.

9

Markers of bone metabolism and survival in men with hormone-refractory metastatic prostate cancer.

Cook RJ, Coleman R, Brown J, Lipton A, Major P, Hei YJ, Saad F, Smith MR. Cook RJ, et al. Clin Cancer Res. 2006 Jun 1;12(11 Pt 1):3361-7. doi: 10.1158/1078-0432.CCR-06-0269. Clin Cancer Res. 2006. PMID: 16740758 Clinical Trial.

10

Tumour vasculature: Friend or foe of oncolytic viruses?

Santry LA, van Vloten JP, Knapp JP, Matuszewska K, McAusland TM, Minott JA, Mould RC, Stegelmeier AA, Major PP, Wootton SK, Petrik JJ, Bridle BW. Santry LA, et al. Among authors: major pp. Cytokine Growth Factor Rev. 2020 Dec;56:69-82. doi: 10.1016/j.cytogfr.2020.07.007. Epub 2020 Sep 1. Cytokine Growth Factor Rev. 2020. PMID: 32893095 Review.

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