Major MB - Search Results

1

Computer-Aided Design and Synthesis of 1-{4-[(3,4-Dihydroxybenzylidene)amino]phenyl}-5-oxopyrrolidine-3-carboxylic Acid as an Nrf2 Enhancer.

Kahremany S, Babaev I, Hasin P, Tamir TY, Ben-Zur T, Cohen G, Jiang Z, Weintraub S, Offen D, Rahimipour S, Major MB, Senderowitz H, Gruzman A. Kahremany S, et al. Among authors: major mb. Chempluschem. 2018 May;83(5):318. doi: 10.1002/cplu.201800155. Epub 2018 Apr 6. Chempluschem. 2018. PMID: 31957368

2

Identification and Characterization of MCM3 as a Kelch-like ECH-associated Protein 1 (KEAP1) Substrate.

Mulvaney KM, Matson JP, Siesser PF, Tamir TY, Goldfarb D, Jacobs TM, Cloer EW, Harrison JS, Vaziri C, Cook JG, Major MB. Mulvaney KM, et al. Among authors: major mb. J Biol Chem. 2016 Nov 4;291(45):23719-23733. doi: 10.1074/jbc.M116.729418. Epub 2016 Sep 12. J Biol Chem. 2016. PMID: 27621311 Free PMC article.

3

The Cancer/Testes (CT) Antigen HORMAD1 promotes Homologous Recombinational DNA Repair and Radioresistance in Lung adenocarcinoma cells.

Gao Y, Kardos J, Yang Y, Tamir TY, Mutter-Rottmayer E, Weissman B, Major MB, Kim WY, Vaziri C. Gao Y, et al. Among authors: major mb. Sci Rep. 2018 Oct 17;8(1):15304. doi: 10.1038/s41598-018-33601-w. Sci Rep. 2018. PMID: 30333500 Free PMC article.

4

WNT Activates the AAK1 Kinase to Promote Clathrin-Mediated Endocytosis of LRP6 and Establish a Negative Feedback Loop.

Agajanian MJ, Walker MP, Axtman AD, Ruela-de-Sousa RR, Serafin DS, Rabinowitz AD, Graham DM, Ryan MB, Tamir T, Nakamichi Y, Gammons MV, Bennett JM, Couñago RM, Drewry DH, Elkins JM, Gileadi C, Gileadi O, Godoi PH, Kapadia N, Müller S, Santiago AS, Sorrell FJ, Wells CI, Fedorov O, Willson TM, Zuercher WJ, Major MB. Agajanian MJ, et al. Among authors: major mb. Cell Rep. 2019 Jan 2;26(1):79-93.e8. doi: 10.1016/j.celrep.2018.12.023. Cell Rep. 2019. PMID: 30605688 Free PMC article.

5

The MyMOMA domain of MYO19 encodes for distinct Miro-dependent and Miro-independent mechanisms of interaction with mitochondrial membranes.

Bocanegra JL, Fujita BM, Melton NR, Cowan JM, Schinski EL, Tamir TY, Major MB, Quintero OA. Bocanegra JL, et al. Among authors: major mb. Cytoskeleton (Hoboken). 2020 Mar;77(3-4):149-166. doi: 10.1002/cm.21560. Epub 2019 Sep 14. Cytoskeleton (Hoboken). 2020. PMID: 31479585 Free PMC article.

6

Computer-Aided Design and Synthesis of 1-{4-[(3,4-Dihydroxybenzylidene)amino]phenyl}-5-oxopyrrolidine-3-carboxylic Acid as an Nrf2 Enhancer.

Kahremany S, Babaev I, Hasin P, Tamir TY, Ben-Zur T, Cohen G, Jiang Z, Weintraub S, Offen D, Rahimipour S, Major MB, Senderowitz H, Gruzman A. Kahremany S, et al. Among authors: major mb. Chempluschem. 2018 May;83(5):320-333. doi: 10.1002/cplu.201700539. Epub 2018 Mar 8. Chempluschem. 2018. PMID: 31957349

7

Gain-of-function genetic screen of the kinome reveals BRSK2 as an inhibitor of the NRF2 transcription factor.

Tamir TY, Bowman BM, Agajanian MJ, Goldfarb D, Schrank TP, Stohrer T, Hale AE, Siesser PF, Weir SJ, Murphy RM, LaPak KM, Weissman BE, Moorman NJ, Major MB. Tamir TY, et al. Among authors: major mb. J Cell Sci. 2020 Jul 15;133(14):jcs241356. doi: 10.1242/jcs.241356. J Cell Sci. 2020. PMID: 32546533 Free PMC article.

8

A conditional mouse expressing an activating mutation in NRF2 displays hyperplasia of the upper gastrointestinal tract and decreased white adipose tissue.

Bowman BM, Montgomery SA, Schrank TP, Simon JM, Ptacek TS, Tamir TY, Mulvaney KM, Weir SJ, Nguyen TT, Murphy RM, Makowski L, Hayes DN, Chen XL, Randell SH, Weissman BE, Major MB. Bowman BM, et al. Among authors: major mb. J Pathol. 2020 Oct;252(2):125-137. doi: 10.1002/path.5504. Epub 2020 Aug 29. J Pathol. 2020. PMID: 32619021 Free PMC article.

9

PKIS deep dive yields a chemical starting point for dark kinases and a cell active BRSK2 inhibitor.

Tamir TY, Drewry DH, Wells C, Major MB, Axtman AD. Tamir TY, et al. Among authors: major mb. Sci Rep. 2020 Sep 28;10(1):15826. doi: 10.1038/s41598-020-72869-9. Sci Rep. 2020. PMID: 32985588 Free PMC article.

10

NRF2 Activation in Cancer: From DNA to Protein.

Cloer EW, Goldfarb D, Schrank TP, Weissman BE, Major MB. Cloer EW, et al. Among authors: major mb. Cancer Res. 2019 Mar 1;79(5):889-898. doi: 10.1158/0008-5472.CAN-18-2723. Epub 2019 Feb 13. Cancer Res. 2019. PMID: 30760522 Free PMC article. Review.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

91 results

Search Page