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Page 1
Simultaneous targeting of mitochondrial Kv1.3 and lysosomal acid sphingomyelinase amplifies killing of pancreatic ductal adenocarcinoma cells in vitro and in vivo.
Patel SH, Bachmann M, Kadow S, Wilson GC, Abdel-Salam MML, Xu K, Keitsch S, Soddemann M, Wilker B, Becker KA, Carpinteiro A, Ahmad SA, Szabo I, Gulbins E. Patel SH, et al. Among authors: bachmann m. J Mol Med (Berl). 2023 Mar;101(3):295-310. doi: 10.1007/s00109-023-02290-y. Epub 2023 Feb 15. J Mol Med (Berl). 2023. PMID: 36790532 Free PMC article.
Pharmacological targeting of the mitochondrial calcium-dependent potassium channel KCa3.1 triggers cell death and reduces tumor growth and metastasis in vivo.
Bachmann M, Rossa A, Varanita T, Fioretti B, Biasutto L, Milenkovic S, Checchetto V, Peruzzo R, Ahmad SA, Patel SH, Lukowski R, Edwards MJ, Ceccarelli M, Gulbins E, Zoratti M, Mattarei A, Szabo I. Bachmann M, et al. Cell Death Dis. 2022 Dec 20;13(12):1055. doi: 10.1038/s41419-022-05463-8. Cell Death Dis. 2022. PMID: 36539400 Free PMC article.
Inhibition of a Mitochondrial Potassium Channel in Combination with Gemcitabine and Abraxane Drastically Reduces Pancreatic Ductal Adenocarcinoma in an Immunocompetent Orthotopic Murine Model.
Li W, Wilson GC, Bachmann M, Wang J, Mattarei A, Paradisi C, Edwards MJ, Szabo I, Gulbins E, Ahmad SA, Patel SH. Li W, et al. Among authors: bachmann m. Cancers (Basel). 2022 May 25;14(11):2618. doi: 10.3390/cancers14112618. Cancers (Basel). 2022. PMID: 35681598 Free PMC article.
Pharmacological modulation of Kv1.3 potassium channel selectively triggers pathological B lymphocyte apoptosis in vivo in a genetic CLL model.
Severin F, Urbani A, Varanita T, Bachmann M, Azzolini M, Martini V, Pizzi M, Tos APD, Frezzato F, Mattarei A, Ghia P, Bertilaccio MTS, Gulbins E, Paradisi C, Zoratti M, Semenzato GC, Leanza L, Trentin L, Szabò I. Severin F, et al. Among authors: bachmann m. J Exp Clin Cancer Res. 2022 Feb 16;41(1):64. doi: 10.1186/s13046-022-02249-w. J Exp Clin Cancer Res. 2022. PMID: 35172855 Free PMC article.
Voltage-Gated Potassium Channels as Regulators of Cell Death.
Bachmann M, Li W, Edwards MJ, Ahmad SA, Patel S, Szabo I, Gulbins E. Bachmann M, et al. Front Cell Dev Biol. 2020 Dec 14;8:611853. doi: 10.3389/fcell.2020.611853. eCollection 2020. Front Cell Dev Biol. 2020. PMID: 33381507 Free PMC article. Review.
19 results