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Anti-ORAI1 antibody DS-2741a, a specific CRAC channel blocker, shows ideal therapeutic profiles for allergic disease via suppression of aberrant T-cell and mast cell activation.
Aki A, Tanaka K, Nagaoka N, Kimura T, Baba D, Onodera Y, Wada T, Maeda H, Nakanishi T, Agatsuma T, Komai T. Aki A, et al. Among authors: maeda h. FASEB Bioadv. 2020 Jul 8;2(8):478-488. doi: 10.1096/fba.2020-00008. eCollection 2020 Aug. FASEB Bioadv. 2020. PMID: 32821879 Free PMC article.
Design of 2'-O-methyl RNA and DNA double-stranded oligonucleotides: naturally-occurring nucleotide components with strong RNA interference gene expression inhibitory activity.
Koizumi M, Hirota Y, Nakayama M, Tamura M, Obuchi W, Kurimoto A, Tsuchida H, Maeda H. Koizumi M, et al. Among authors: maeda h. Nucleosides Nucleotides Nucleic Acids. 2020;39(1-3):292-309. doi: 10.1080/15257770.2019.1663384. Epub 2019 Sep 11. Nucleosides Nucleotides Nucleic Acids. 2020. PMID: 31509065
Discovery and pharmacological effects of a novel GPR142 antagonist.
Murakoshi M, Kuwabara H, Nagasaki M, Xiong YM, Reagan JD, Maeda H, Nara F. Murakoshi M, et al. Among authors: maeda h. J Recept Signal Transduct Res. 2017 Jun;37(3):290-296. doi: 10.1080/10799893.2016.1247861. Epub 2016 Nov 3. J Recept Signal Transduct Res. 2017. PMID: 27807998
3,964 results