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Immune checkpoint inhibitor-induced colitis is mediated by polyfunctional lymphocytes and is dependent on an IL23/IFNγ axis.
Lo JW, Cozzetto D, Alexander JL, Danckert NP, Madgwick M, Knox N, Sieh JYX, Olbei M, Liu Z, Ibraheim H, Blanco JM, Kudo H, Seoane RC, Possamai LA, Goldin R, Marchesi J, Korcsmaros T, Lord GM, Powell N. Lo JW, et al. Among authors: madgwick m. Nat Commun. 2023 Oct 23;14(1):6719. doi: 10.1038/s41467-023-41798-2. Nat Commun. 2023. PMID: 37872166 Free PMC article.
AutophagyNet: high-resolution data source for the analysis of autophagy and its regulation.
Csabai L, Bohár B, Türei D, Prabhu S, Földvári-Nagy L, Madgwick M, Fazekas D, Módos D, Ölbei M, Halka T, Poletti M, Kornilova P, Kadlecsik T, Demeter A, Szalay-Bekő M, Kapuy O, Lenti K, Vellai T, Gul L, Korcsmáros T. Csabai L, et al. Among authors: madgwick m. Autophagy. 2024 Jan;20(1):188-201. doi: 10.1080/15548627.2023.2247737. Epub 2023 Aug 17. Autophagy. 2024. PMID: 37589496 Free PMC article.
Interleukin-22 regulates neutrophil recruitment in ulcerative colitis and is associated with resistance to ustekinumab therapy.
Pavlidis P, Tsakmaki A, Pantazi E, Li K, Cozzetto D, Digby-Bell J, Yang F, Lo JW, Alberts E, Sa ACC, Niazi U, Friedman J, Long AK, Ding Y, Carey CD, Lamb C, Saqi M, Madgwick M, Gul L, Treveil A, Korcsmaros T, Macdonald TT, Lord GM, Bewick G, Powell N. Pavlidis P, et al. Among authors: madgwick m. Nat Commun. 2022 Oct 3;13(1):5820. doi: 10.1038/s41467-022-33331-8. Nat Commun. 2022. PMID: 36192482 Free PMC article.
Mapping the epithelial-immune cell interactome upon infection in the gut and the upper airways.
Poletti M, Treveil A, Csabai L, Gul L, Modos D, Madgwick M, Olbei M, Bohar B, Valdeolivas A, Turei D, Verstockt B, Triana S, Alexandrov T, Saez-Rodriguez J, Stanifer ML, Boulant S, Korcsmaros T. Poletti M, et al. Among authors: madgwick m. NPJ Syst Biol Appl. 2022 May 2;8(1):15. doi: 10.1038/s41540-022-00224-x. NPJ Syst Biol Appl. 2022. PMID: 35501398 Free PMC article.
A systems genomics approach to uncover patient-specific pathogenic pathways and proteins in ulcerative colitis.
Brooks-Warburton J, Modos D, Sudhakar P, Madgwick M, Thomas JP, Bohar B, Fazekas D, Zoufir A, Kapuy O, Szalay-Beko M, Verstockt B, Hall LJ, Watson A, Tremelling M, Parkes M, Vermeire S, Bender A, Carding SR, Korcsmaros T. Brooks-Warburton J, et al. Among authors: madgwick m. Nat Commun. 2022 Apr 28;13(1):2299. doi: 10.1038/s41467-022-29998-8. Nat Commun. 2022. PMID: 35484353 Free PMC article.
Extracellular vesicles produced by the human commensal gut bacterium Bacteroides thetaiotaomicron affect host immune pathways in a cell-type specific manner that are altered in inflammatory bowel disease.
Gul L, Modos D, Fonseca S, Madgwick M, Thomas JP, Sudhakar P, Booth C, Stentz R, Carding SR, Korcsmaros T. Gul L, et al. Among authors: madgwick m. J Extracell Vesicles. 2022 Jan;11(1):e12189. doi: 10.1002/jev2.12189. J Extracell Vesicles. 2022. PMID: 35064769 Free PMC article.
SignaLink3: a multi-layered resource to uncover tissue-specific signaling networks.
Csabai L, Fazekas D, Kadlecsik T, Szalay-Bekő M, Bohár B, Madgwick M, Módos D, Ölbei M, Gul L, Sudhakar P, Kubisch J, Oyeyemi OJ, Liska O, Ari E, Hotzi B, Billes VA, Molnár E, Földvári-Nagy L, Csályi K, Demeter A, Pápai N, Koltai M, Varga M, Lenti K, Farkas IJ, Türei D, Csermely P, Vellai T, Korcsmáros T. Csabai L, et al. Among authors: madgwick m. Nucleic Acids Res. 2022 Jan 7;50(D1):D701-D709. doi: 10.1093/nar/gkab909. Nucleic Acids Res. 2022. PMID: 34634810 Free PMC article.
Antibiotic-induced disturbances of the gut microbiota result in accelerated breast tumor growth.
McKee AM, Kirkup BM, Madgwick M, Fowler WJ, Price CA, Dreger SA, Ansorge R, Makin KA, Caim S, Le Gall G, Paveley J, Leclaire C, Dalby M, Alcon-Giner C, Andrusaite A, Feng TY, Di Modica M, Triulzi T, Tagliabue E, Milling SWF, Weilbaecher KN, Rutkowski MR, Korcsmáros T, Hall LJ, Robinson SD. McKee AM, et al. Among authors: madgwick m. iScience. 2021 Aug 20;24(9):103012. doi: 10.1016/j.isci.2021.103012. eCollection 2021 Sep 24. iScience. 2021. PMID: 34522855 Free PMC article.
13 results