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Targeting MET and EGFR crosstalk signaling in triple-negative breast cancers.
Linklater ES, Tovar EA, Essenburg CJ, Turner L, Madaj Z, Winn ME, Melnik MK, Korkaya H, Maroun CR, Christensen JG, Steensma MR, Boerner JL, Graveel CR. Linklater ES, et al. Oncotarget. 2016 Oct 25;7(43):69903-69915. doi: 10.18632/oncotarget.12065. Oncotarget. 2016. PMID: 27655711 Free PMC article.
Glesatinib Exhibits Antitumor Activity in Lung Cancer Models and Patients Harboring MET Exon 14 Mutations and Overcomes Mutation-mediated Resistance to Type I MET Inhibitors in Nonclinical Models.
Engstrom LD, Aranda R, Lee M, Tovar EA, Essenburg CJ, Madaj Z, Chiang H, Briere D, Hallin J, Lopez-Casas PP, Baños N, Menendez C, Hidalgo M, Tassell V, Chao R, Chudova DI, Lanman RB, Olson P, Bazhenova L, Patel SP, Graveel C, Nishino M, Shapiro GI, Peled N, Awad MM, Jänne PA, Christensen JG. Engstrom LD, et al. Clin Cancer Res. 2017 Nov 1;23(21):6661-6672. doi: 10.1158/1078-0432.CCR-17-1192. Epub 2017 Aug 1. Clin Cancer Res. 2017. PMID: 28765324 Clinical Trial.
Genomic Status of MET Potentiates Sensitivity to MET and MEK Inhibition in NF1-Related Malignant Peripheral Nerve Sheath Tumors.
Peacock JD, Pridgeon MG, Tovar EA, Essenburg CJ, Bowman M, Madaj Z, Koeman J, Boguslawski EA, Grit J, Dodd RD, Khachaturov V, Cardona DM, Chen M, Kirsch DG, Maina F, Dono R, Winn ME, Graveel CR, Steensma MR. Peacock JD, et al. Cancer Res. 2018 Jul 1;78(13):3672-3687. doi: 10.1158/0008-5472.CAN-17-3167. Epub 2018 May 2. Cancer Res. 2018. PMID: 29720369 Free PMC article.
NF1 deficiency correlates with estrogen receptor signaling and diminished survival in breast cancer.
Dischinger PS, Tovar EA, Essenburg CJ, Madaj ZB, Gardner EE, Callaghan ME, Turner AN, Challa AK, Kempston T, Eagleson B, Kesterson RA, Bronson RT, Bowman MJ, Graveel CR, Steensma MR. Dischinger PS, et al. Among authors: madaj zb. NPJ Breast Cancer. 2018 Aug 30;4:29. doi: 10.1038/s41523-018-0080-8. eCollection 2018. NPJ Breast Cancer. 2018. PMID: 30182054 Free PMC article.
An inflammatory profile linked to increased suicide risk.
Keaton SA, Madaj ZB, Heilman P, Smart L, Grit J, Gibbons R, Postolache TT, Roaten K, Achtyes ED, Brundin L. Keaton SA, et al. Among authors: madaj zb. J Affect Disord. 2019 Mar 15;247:57-65. doi: 10.1016/j.jad.2018.12.100. Epub 2019 Jan 3. J Affect Disord. 2019. PMID: 30654266 Free PMC article.
Altered Tryptophan Catabolism in Placentas From Women With Pre-eclampsia.
Keaton SA, Heilman P, Bryleva EY, Madaj Z, Krzyzanowski S, Grit J, Miller ES, Jälmby M, Kalapotharakos G, Racicot K, Fazleabas A, Hansson SR, Brundin L. Keaton SA, et al. Int J Tryptophan Res. 2019 Apr 8;12:1178646919840321. doi: 10.1177/1178646919840321. eCollection 2019. Int J Tryptophan Res. 2019. PMID: 31007529 Free PMC article.
53 results