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The relevance of a digestibility evaluation in the allergenicity risk assessment of novel proteins. Opinion of a joint initiative of COST action ImpARAS and COST action INFOGEST.
Verhoeckx K, Bøgh KL, Dupont D, Egger L, Gadermaier G, Larré C, Mackie A, Menard O, Adel-Patient K, Picariello G, Portmann R, Smit J, Turner P, Untersmayr E, Epstein MM. Verhoeckx K, et al. Among authors: mackie a. Food Chem Toxicol. 2019 Jul;129:405-423. doi: 10.1016/j.fct.2019.04.052. Epub 2019 May 4. Food Chem Toxicol. 2019. PMID: 31063834 Free article.
In vitro digestibility of beta-casein and beta-lactoglobulin under simulated human gastric and duodenal conditions: a multi-laboratory evaluation.
Mandalari G, Adel-Patient K, Barkholt V, Baro C, Bennett L, Bublin M, Gaier S, Graser G, Ladics GS, Mierzejewska D, Vassilopoulou E, Vissers YM, Zuidmeer L, Rigby NM, Salt LJ, Defernez M, Mulholland F, Mackie AR, Wickham MS, Mills EN. Mandalari G, et al. Among authors: mackie ar. Regul Toxicol Pharmacol. 2009 Dec;55(3):372-81. doi: 10.1016/j.yrtph.2009.08.010. Epub 2009 Aug 31. Regul Toxicol Pharmacol. 2009. PMID: 19723552
Effect of heating and glycation on the allergenicity of 2S albumins (Ara h 2/6) from peanut.
Vissers YM, Blanc F, Skov PS, Johnson PE, Rigby NM, Przybylski-Nicaise L, Bernard H, Wal JM, Ballmer-Weber B, Zuidmeer-Jongejan L, Szépfalusi Z, Ruinemans-Koerts J, Jansen AP, Savelkoul HF, Wichers HJ, Mackie AR, Mills CE, Adel-Patient K. Vissers YM, et al. PLoS One. 2011;6(8):e23998. doi: 10.1371/journal.pone.0023998. Epub 2011 Aug 25. PLoS One. 2011. PMID: 21901150 Free PMC article.
Boiling peanut Ara h 1 results in the formation of aggregates with reduced allergenicity.
Blanc F, Vissers YM, Adel-Patient K, Rigby NM, Mackie AR, Gunning AP, Wellner NK, Skov PS, Przybylski-Nicaise L, Ballmer-Weber B, Zuidmeer-Jongejan L, Szépfalusi Z, Ruinemans-Koerts J, Jansen AP, Bernard H, Wal JM, Savelkoul HF, Wichers HJ, Mills EN. Blanc F, et al. Among authors: mackie ar. Mol Nutr Food Res. 2011 Dec;55(12):1887-94. doi: 10.1002/mnfr.201100251. Epub 2011 Nov 16. Mol Nutr Food Res. 2011. PMID: 22086730
595 results