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Page 1
Efficacy and safety of vismodegib in advanced basal-cell carcinoma.
N Engl J Med. 2012 Jun 7;366(23):2171-9. doi: 10.1056/NEJMoa1113713.
N Engl J Med. 2012.
PMID: 22670903
Free PMC article.
Clinical Trial.
Inhibition of the hedgehog pathway in advanced basal-cell carcinoma.
Von Hoff DD, LoRusso PM, Rudin CM, Reddy JC, Yauch RL, Tibes R, Weiss GJ, Borad MJ, Hann CL, Brahmer JR, Mackey HM, Lum BL, Darbonne WC, Marsters JC Jr, de Sauvage FJ, Low JA.
Von Hoff DD, et al. Among authors: mackey hm.
N Engl J Med. 2009 Sep 17;361(12):1164-72. doi: 10.1056/NEJMoa0905360. Epub 2009 Sep 2.
N Engl J Med. 2009.
PMID: 19726763
Free article.
Clinical Trial.
Item in Clipboard
A randomized phase II trial of vismodegib versus placebo with FOLFOX or FOLFIRI and bevacizumab in patients with previously untreated metastatic colorectal cancer.
Berlin J, Bendell JC, Hart LL, Firdaus I, Gore I, Hermann RC, Mulcahy MF, Zalupski MM, Mackey HM, Yauch RL, Graham RA, Bray GL, Low JA.
Berlin J, et al. Among authors: mackey hm.
Clin Cancer Res. 2013 Jan 1;19(1):258-67. doi: 10.1158/1078-0432.CCR-12-1800. Epub 2012 Oct 18.
Clin Cancer Res. 2013.
PMID: 23082002
Clinical Trial.
Item in Clipboard
Phase II study of bevacizumab in patients with platinum-resistant ovarian cancer or peritoneal serous cancer.
Cannistra SA, Matulonis UA, Penson RT, Hambleton J, Dupont J, Mackey H, Douglas J, Burger RA, Armstrong D, Wenham R, McGuire W.
Cannistra SA, et al.
J Clin Oncol. 2007 Nov 20;25(33):5180-6. doi: 10.1200/JCO.2007.12.0782.
J Clin Oncol. 2007.
PMID: 18024865
Clinical Trial.
Item in Clipboard
Some notable properties of the standard oncology Phase I design.
Hather GJ, Mackey H.
Hather GJ, et al.
J Biopharm Stat. 2009;19(3):543-55. doi: 10.1080/10543400902802466.
J Biopharm Stat. 2009.
PMID: 19384695
Item in Clipboard
Sample size and threshold estimation for clinical trials with predictive biomarkers.
Mackey HM, Bengtsson T.
Mackey HM, et al.
Contemp Clin Trials. 2013 Nov;36(2):664-72. doi: 10.1016/j.cct.2013.09.005. Epub 2013 Sep 21.
Contemp Clin Trials. 2013.
PMID: 24064355
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Tissue effects on the expression of serotonin, tyrosine hydroxylase and GABA in cultures of neurogenic cells from the neuraxis and branchial arches.
Mackey HM, Payette RF, Gershon MD.
Mackey HM, et al.
Development. 1988 Oct;104(2):205-17. doi: 10.1242/dev.104.2.205.
Development. 1988.
PMID: 2908201
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